Successful pregnancy and follow-up after in vitro fertilization of a kidney transplant patient with systemic lupus erythematosus, primary biliary cholangitis, and hypothyroidism

This report describes the case of a female kidney transplant patient with systemic lupus erythematosus, primary biliary cholangitis, and postsurgical hypothyroidism due to Grave's disease who had a healthy newborn after in vitro fertilization (IVF). Cases of successful pregnancy involving women...

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Bibliographic Details
Published in:JBRA assisted reproduction 2021, Vol.25 (4), p.657-660
Main Authors: Gastañaga-Holguera, Teresa, Calvo, Marta, Gómez-Irwin, Laura, Gesto, Isabel Campo, González-González, Virginia, Vidaurreta, Marta
Format: Article
Language:English
Subjects:
Antibodies
Art therapy
Birth weight
Blood pressure
Case Report
Cholangitis
Disease
Female
Fertilization in Vitro
Follow-Up Studies
Hormone replacement therapy
Humans
Hypertension
Hypothyroidism
Hypothyroidism - complications
Immunosuppressive agents
In vitro fertilization
Infant, Newborn
Infertility
Kidney Transplantation - adverse effects
Kidney transplants
Liver cirrhosis
Liver Cirrhosis, Biliary - complications
Liver Cirrhosis, Biliary - surgery
Lupus
Lupus Erythematosus, Systemic - complications
Obstetrics
Ovaries
Patients
Preeclampsia
Pregnancy
Reproductive technologies
Umbilical cord
Vagina
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Summary:This report describes the case of a female kidney transplant patient with systemic lupus erythematosus, primary biliary cholangitis, and postsurgical hypothyroidism due to Grave's disease who had a healthy newborn after in vitro fertilization (IVF). Cases of successful pregnancy involving women who underwent IVF after kidney transplantation have been reported. Normal and stable renal function, adequate immunosuppressant therapy, and well-managed blood pressure are requirements to be eligible for IVF and pregnancy. Primary biliary cholangitis without cirrhosis does not seem to worsen during pregnancy and IVF must be individualized in patients with systemic lupus erythematosus. There are no similar case reports involving kidney transplant patients or individuals with autoimmune disorders, so the decision to perform IVF had to be individualized in order to avoid complications for the mother and fetus.
ISSN:1518-0557
1517-5693
1518-0557
DOI:10.5935/1518-0557.20210052