Pseudohypocalcemia in Cancer Patients: A Recommendation for the Postanalytical Correction of Serum Calcium in Patients with Hypoalbuminemia

A retrospective institutional review board-approved study was performed to evaluate the accuracy of calcium correction in estimating true critically low calcium events in cancer patients with hypoalbuminemia. Author Contributions: Allauthors confirmed they have contributed to the intellectual conten...

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Bibliographic Details
Published in:Clinical chemistry (Baltimore, Md.) Md.), 2017-07, Vol.63 (7), p.1302-1304
Main Authors: Carroll, Brittany, Fleisher, Martin, Pessin, Melissa S, Richardson, Shaun, Ramanathan, Lakshmi V
Format: Article
Language:English
Subjects:
Calcium
Calcium - blood
Cancer
Humans
Hypoalbuminemia - blood
Laboratories
Metabolism
Neoplasms - blood
Patients
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Summary:A retrospective institutional review board-approved study was performed to evaluate the accuracy of calcium correction in estimating true critically low calcium events in cancer patients with hypoalbuminemia. Author Contributions: Allauthors confirmed they have contributed to the intellectual content of this paper and have met the following 3 requirements: (a) significant contributions to the conception and design, acquisition of data, or analysis and interpretation ofdata; (b) drafting or revising the article for intellectual content; and (c) final approval ofthe published article. Patents: None declared. ©2017 American Association for Clinical Chemistry Brittany Carroll2 Martin Fleisher2 Melissa S. Pessin2 Shaun Richardson2 Lakshmi V. Ramanathan2· Previously published online at DOI: 10.1373/clinchem.2017.272997 1 Nonstandard abbreviations: MSKCC, Memorial Sloan Kettering Cancer Center; RI, reference interval; CMP comprehensive metabolic panel. 2 Department of Laboratory Medicine Memorial Sloan Kettering Cancer Center New York, NY "Address correspondence to this author at:
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2017.272997