Optimizing Operating Parameters of Electric Ultra-Low Volume Sprayer with Slightly Acidic Electrolyzed Solution for Efficient Virucidal Activity on Environmental Surfaces

Recently, and considering the COVID-19 pandemic, there has been a growing consensus that the disinfection of surfaces contaminated with pathogenic viral particles is essential. Chemical disinfectant sprays are effective at preventing the spread of infectious human noroviruses (Hu-NoVs) in healthcare...

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Bibliographic Details
Published in:International journal of environmental research and public health 2021-09, Vol.18 (19), p.10183
Main Authors: Lee, Hae-Won, Yoon, So-Ra, Song, Hyeyeon, Park, Boyeon, Ha, Ji-Hyoung
Format: Article
Language:English
Subjects:
Antiseptics
Chlorine
COVID-19
Decontamination
Disease control
Disease transmission
Disinfectants
Disinfection
Disinfection & disinfectants
Epidemics
Hydrochloric acid
Infectious diseases
Oxidation
Oxidation-reduction potential
Pathogens
Polyvinyl chloride
Public health
Response surface methodology
Software
Sprayers
Spraying
Sprays
Stainless steel
Viruses
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Summary:Recently, and considering the COVID-19 pandemic, there has been a growing consensus that the disinfection of surfaces contaminated with pathogenic viral particles is essential. Chemical disinfectant sprays are effective at preventing the spread of infectious human noroviruses (Hu-NoVs) in healthcare and public areas. We assessed the virucidal activity of slightly acidic electrolyzed water (SAEW) spray on fomite surfaces. A multivariate statistical assessment that combined a response surface methodology (RSM) and a Box–Behnken design (BBD) was performed to define the optimal parameters of, and correlations among, experimental conditions. Spraying SAEW disinfectant (oxidation-reduction potential: 1123 mV, pH range: 5.12, available chlorine concentration: 33.22 ppm) resulted in the successful decontamination of Hu-NoV, with a 4-log reduction in viral particles on polyvinyl chloride, stainless steel, ceramic tile, and glass surfaces. Our experimental data revealed optimized treatment conditions for decontaminating Hu-NoV GI.6 and GII.4, using the numerical multiple optimized method (spraying rate: 218 mL/min, spraying time: 4.9 s, spraying distance: 0.9 m). These findings offer significant insights for designing optimal strategic control practices to prevent infectious disease, particularly Hu-NoV, transmission.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph181910183