PARN-like Proteins Regulate Gene Expression in Land Plant Mitochondria by Modulating mRNA Polyadenylation

Mitochondria have their own double-stranded DNA genomes and systems to regulate transcription, mRNA processing, and translation. These systems differ from those operating in the host cell, and among eukaryotes. In recent decades, studies have revealed several plant-specific features of mitochondrial...

Full description

Saved in:
Bibliographic Details
Published in:International journal of molecular sciences 2021-10, Vol.22 (19), p.10776
Main Author: Hirayama, Takashi
Format: Article
Language:English
Subjects:
Bacteria
Communication
Cytoplasm
Enzymes
Eukaryotes
Gene expression
Gene regulation
Genomes
Metabolism
Metabolites
Mitochondria
mRNA processing
Plant mitochondria
Poly(A)
Poly(A)-specific ribonuclease
Polyadenylation
Proteins
Quality control
Review
RNA polymerase
Transcription
Translation
Yeast
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Mitochondria have their own double-stranded DNA genomes and systems to regulate transcription, mRNA processing, and translation. These systems differ from those operating in the host cell, and among eukaryotes. In recent decades, studies have revealed several plant-specific features of mitochondrial gene regulation. The polyadenylation status of mRNA is critical for its stability and translation in mitochondria. In this short review, I focus on recent advances in understanding the mechanisms regulating mRNA polyadenylation in plant mitochondria, including the role of poly(A)-specific ribonuclease-like proteins (PARNs). Accumulating evidence suggests that plant mitochondria have unique regulatory systems for mRNA poly(A) status and that PARNs play pivotal roles in these systems.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms221910776