Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2021-09, Vol.204 (6), p.731-734
Main Authors: Couillard, Simon, Shrimanker, Rahul, Chaudhuri, Rekha, Mansur, Adel H, McGarvey, Lorcan P, Heaney, Liam G, Fowler, Stephen J, Bradding, Peter, Pavord, Ian D, Hinks, Timothy S C
Format: Article
Language:English
Subjects:
Administration, Inhalation
Adrenal Cortex Hormones - therapeutic use
Adult
Aged
Anti-Asthmatic Agents - therapeutic use
Asthma - diagnosis
Asthma - drug therapy
Asthma - metabolism
Biomarkers - analysis
Biomarkers - metabolism
Breath Tests
Case-Control Studies
Correspondence
Cross-Sectional Studies
Drug Resistance
Eosinophils - metabolism
Exhalation
Female
Humans
Male
Middle Aged
Nitric Oxide - analysis
Nitric Oxide - metabolism
Severity of Illness Index
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ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.202104-1040LE