Fiber endface photoacoustic generator for quantitative photoacoustic tomography

We demonstrate a novel fiber endface photoacoustic (PA) generator using infrared (IR) 144 laser dye dispersed within an ultraviolet adhesive. The generator provides a wide acoustic bandwidth in the transducer frequency range of 2–7 MHz, high thermal conversion efficiency ( > 90 % ), good PA signa...

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Bibliographic Details
Published in:Optics letters 2021-06, Vol.46 (11), p.2706-2709
Main Authors: Yang, Guang, Huang, Hengbo, Luo, Hongbo, Kou, Sitai, Amidi, Eghbal, Achilefu, Samuel, Zhu, Quing
Format: Article
Language:English
Subjects:
Absorptivity
Biomedical materials
Controllability
Frequency ranges
Infrared lasers
Photoacoustic effect
Stability
Tissues
Tomography
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Description
Summary:We demonstrate a novel fiber endface photoacoustic (PA) generator using infrared (IR) 144 laser dye dispersed within an ultraviolet adhesive. The generator provides a wide acoustic bandwidth in the transducer frequency range of 2–7 MHz, high thermal conversion efficiency ( > 90 % ), good PA signal controllability (well-controlled IR 144 concentration), and high feasibility (simple procedures). Through a series of experimental validations, we show that this fiber-based endface PA generator can be a useful tool for a broad range of biomedical applications such as calibrating the local absorption coefficient of biological tissue for quantitative PA tomography.
ISSN:0146-9592
1539-4794
DOI:10.1364/OL.426033