Effect of Prepregnancy Lymphocyte Active Immunotherapy on Unexplained Recurrent Miscarriage, Pregnancy Success Rate, and Maternal-Infant Outcome

Objective. To evaluate the effect of prepregnancy lymphocyte active immunotherapy on unexplained recurrent miscarriage, pregnancy success rate, and maternal-infant outcome. Methods. A total of 124 patients with recurrent miscarriage admitted to our hospital from January 2018 to December 2020 were se...

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Bibliographic Details
Published in:BioMed research international 2021-10, Vol.2021, p.7878752-6
Main Authors: Li, Junxia, Gu, Yan, Zhang, Shaojing, Ju, Baohui, Wang, Jianmei
Format: Article
Language:English
Subjects:
Abortion, Habitual
Abortion, Habitual - drug therapy
Abortion, Habitual - immunology
Abortion, Habitual - pathology
Abortion, Habitual - therapy
Active control
Adult
Analysis
Antibodies
Blood
Case-Control Studies
Efficiency
Estrogens
Female
Health aspects
Humans
Immunization
Immunotherapy
Immunotherapy, Active
Immunotherapy, Adoptive - methods
Infant
Infants
Lymphocyte Activation
Lymphocyte Transfusion
Lymphocytes
Lymphocytes - immunology
Male
Maternal health services
Miscarriage
Mother-Child Relations - psychology
Patient outcomes
Patients
Physiological aspects
Pregnancy
Pregnancy Outcome
Pregnancy Rate
Pregnant women
Prevention
Progesterone - administration & dosage
Random numbers
Retrospective Studies
Risk factors
Software
Success
Citations: Items that this one cites
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Summary:Objective. To evaluate the effect of prepregnancy lymphocyte active immunotherapy on unexplained recurrent miscarriage, pregnancy success rate, and maternal-infant outcome. Methods. A total of 124 patients with recurrent miscarriage admitted to our hospital from January 2018 to December 2020 were selected as the research objects and divided into the experimental group and the control group according to the random number table method, with 62 patients in each group. The experimental group was treated with lymphocyte active immunotherapy, and the control group was given conventional treatment. The pregnancy success rate, estrogen indexes, hemorheology indexes, and psychological state of the two groups were compared. Results. The experimental group garnered a notably higher pregnancy success rate and a prominently lower miscarriage rate than the control group (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2021/7878752