Nasal oral fistula revealing Langerhans' cell histiocytosis in adult patient: case report

Langerhans cell histiocytosis (LCH) is a rare systemic disease caused by proliferation of mature histiocytes; its association to histiocyto fibroma is rarely reported. It rarely affects adults. We report a case of systemic LCH, in an adult patient with osteolytic lesion causing a fistula between the...

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Bibliographic Details
Published in:The Pan African medical journal 2021-09, Vol.40
Main Authors: Mzabi, Anis, Thabet, Maissa, Tlili, Taghrid, Zorgati, Hend, Anoun, Jihed, Hassine, Imen Ben, Karmeni, Monia, Fredj, Fatma Ben, Mokni, Moncef, Laouani, Chadia
Format: Article
Language:English
Subjects:
Adults
Autoimmune diseases
Biopsy
Case Report
Case reports
Chemotherapy
Cysts
Fistula
Lymphatic system
Patients
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Summary:Langerhans cell histiocytosis (LCH) is a rare systemic disease caused by proliferation of mature histiocytes; its association to histiocyto fibroma is rarely reported. It rarely affects adults. We report a case of systemic LCH, in an adult patient with osteolytic lesion causing a fistula between the left nasal cavity and hard palate, involving the bone, lung, lymph node and associated to multiple histiocyto fibroma. The patient was operating for a fistula, and he was treated by chemotherapy and corticosteroids. Langerhans´ cell histiocytosis is a rare case, especially in adult patient. The diagnosis was based on histological and immunohistochemical analyses. This patient was treated by steroids and chemotherapy.
ISSN:1937-8688
1937-8688
DOI:10.11604/pamj.2021.40.16.27074