An Observational Real-Life Study with a New Infant Formula in Infants with Functional Gastro-Intestinal Disorders

Functional gastro-intestinal disorders (FGIDs) impair the quality of life of many infants and their families. A formula with partial whey hydrolysate, starch, high magnesium content, prebiotic fructo-oligosaccharide and galacto-oligosaccharide and the probiotic Lactobacillus reuteri DSM 17938 was gi...

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Bibliographic Details
Published in:Nutrients 2021-09, Vol.13 (10), p.3336
Main Authors: Vandenplas, Yvan, Gerlier, Laetitia, Caekelbergh, Karin, Possner, Mike
Format: Article
Language:English
Subjects:
Antibiotics
Babies
Baby foods
Constipation
Cow's milk
Fructooligosaccharides
Galactooligosaccharides
Hydrolysates
Infantile colic
Infants
Intestine
Magnesium
Milk
Parents & parenting
Pediatrics
Probiotics
Quality of life
Questionnaires
Whey
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Summary:Functional gastro-intestinal disorders (FGIDs) impair the quality of life of many infants and their families. A formula with partial whey hydrolysate, starch, high magnesium content, prebiotic fructo-oligosaccharide and galacto-oligosaccharide and the probiotic Lactobacillus reuteri DSM 17938 was given during two weeks to 196 infants with at least two FGIDs. The efficacy was evaluated with the Cow Milk-associated Symptom Score (CoMiSS®) and quality of life with the QUALIN score. The formula was shown to decrease FGIDs within three days (decrease of CoMiSS −1.29 (3.15) (mean (SD), p < 0.0001) followed by an improvement of quality of life after seven days (increase QUALIN +1.4 (7.8); p: 0.008). Constipation decreased from 18.8% to 6.5% within three days. In combination with reassurance and guidance, the nutritional intervention was shown to be effective in infants with FGIDS in real-life circumstances.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu13103336