Lymphedema in Endometrial Cancer Survivor: A Nationwide Cohort Study

Background: Endometrial cancer is the most common gynecological cancer in developed countries. Treatment-related lymphedema negatively affects the quality of life and function of patients. This study investigated the cumulative incidence and risk factors of, and utilization of health care resources...

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Bibliographic Details
Published in:Journal of clinical medicine 2021-10, Vol.10 (20), p.4647
Main Authors: Lee, Su-Jeong, Myong, Jun-Pyo, Lee, Yun-Hee, Cho, Eui-Jin, Lee, Sung-Jong, Kim, Chan-Joo, Kim, Jin-Hwi
Format: Article
Language:English
Subjects:
Age groups
Breast cancer
Cancer therapies
Chemotherapy
Clinical medicine
Codes
Cohort analysis
Endometrial cancer
Gynecology
Health insurance
Hysterectomy
Lymphatic system
Lymphedema
Medical prognosis
Neighborhoods
Patients
Physical therapy
Population
Radiation therapy
Surgery
Urban areas
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Summary:Background: Endometrial cancer is the most common gynecological cancer in developed countries. Treatment-related lymphedema negatively affects the quality of life and function of patients. This study investigated the cumulative incidence and risk factors of, and utilization of health care resources for, lymphedema in patients with endometrial cancer. Methods: We conducted a nationwide, retrospective cohort study of women with endometrial cancer who underwent cancer-direct treatment using the Korean National Health Insurance Service (NHIS) database. Patients were categorized by age, region, income, and treatment modality. Cox proportional hazards regression models were used to analyze the incidence and risk factors of lymphedema. We also analyzed utilization of health care resources for lymphedema using diagnostic and treatment claim codes. Results: A total of 19,027 patients with endometrial cancer were evaluated between January 2004 and December 2017. Among them, 2493 (13.1%) developed lymphedema. Age (
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm10204647