An Efficient PCA-GA-HKSVM-Based Disease Diagnostic Assistant

• Published in: BioMed research international 2021-10, Vol.2021, p.4784057-10
• Main Authors: Jerop, Brenda, Segera, Davies Rene
• Format: Article
• Language: English
• Subjects: Algorithms; Analysis; Artificial intelligence; Classification; Datasets; Diagnosis; Diagnosis, Differential; Diagnostic Techniques and Procedures - instrumentation; Early Diagnosis; Genetic algorithms; Genetic vectors; Health aspects; Humans; Kernel functions; Kernels; Learning algorithms; Machine Learning; Methods; Neural networks; Optimization; Performance evaluation; Polynomials; Principal Component Analysis - methods; Principal components analysis; Radial basis function; Signs and symptoms; Support Vector Machine; Support vector machines
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2021/4784057

Disease diagnosis faces challenges such as misdiagnosis, lack of diagnosis, and slow diagnosis. There are several machine learning techniques that have been applied to address these challenges, where a set of symptoms is applied to a classification model that predicts the presence or absence of a disease. To improve on the performance of these techniques, this paper presents a technique which involves feature selection using principal component analysis (PCA), a hybrid kernel-based support vector machine (HKSVM) classification model and hyperparameter optimization using genetic algorithm (GA). The HKSVM in this paper introduces a new way of combining three kernels: Radial basis function (RBF), linear, and polynomial. Combining local (RBF) and global (linear and polynomial) kernels has the effect of improved model performance. This is because the local kernels are better able to distinguish points closer to each other while the global kernels are more suited to distinguish points that are far away from each other. The PCA-GA-HKSVM is used on 7 different medical datasets, with two datasets being multiclass datasets and 5 datasets being binary. Performance evaluation metrics used were accuracy, precision, and recall. It was observed that the PCA-GA-HKSVM offered better performance than the single kernel support vector machines (SVMs).