Sex-specific cytokine responses and neurocognitive outcome after blood transfusions in preterm infants

Background The objective of this study was to determine sex-specific differences in inflammatory cytokine responses to red blood cell (RBC) transfusion in preterm infants in the neonatal period and their relationship to later neurocognitive status. Methods Infants with a birth weight

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Bibliographic Details
Published in:Pediatric research 2022-03, Vol.91 (4), p.947-954
Main Authors: Benavides, Amanda, Bell, Edward F., Georgieff, Michael K., Josephson, Cassandra D., Stowell, Sean R., Feldman, Henry A., Nalbant, Demet, Tereshchenko, Alexander, Sola-Visner, Martha, Nopoulos, Peggy
Format: Article
Language:English
Subjects:
Clinical Research Article
Cytokines
Cytokines - metabolism
Erythrocyte Transfusion - adverse effects
Female
Humans
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Male
Medicine
Medicine & Public Health
Neurocognitive Disorders - epidemiology
Newborn babies
Pediatric Surgery
Pediatrics
Premature babies
Sex Distribution
Treatment Outcome
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Description
Summary:Background The objective of this study was to determine sex-specific differences in inflammatory cytokine responses to red blood cell (RBC) transfusion in preterm infants in the neonatal period and their relationship to later neurocognitive status. Methods Infants with a birth weight
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-021-01536-0