Prevention and Treatment of SARS-CoV2 Infection in People Living with HIV: The Need for Specific Data

The HIV pandemic has led to close to 40 million people living with HIV (PLWH) worldwide. To date, SARS-CoV2 has affected > 220 million people, and unprecedented global efforts have resulted in almost 6000 million doses of SARS-CoV2 vaccines being administered. Although several specific COVID-19 a...

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Bibliographic Details
Published in:Infectious diseases and therapy 2022-02, Vol.11 (1), p.1-13
Main Authors: Díaz, Natalia A., de Miguel, Rosa, Agüero, Fernando, Sued, Omar, Arribas, José R., Ambrosioni, Juan
Format: Article
Language:English
Subjects:
Antiviral agents
Care and treatment
Commentary
COVID-19
COVID-19 vaccines
Epidemics
Health aspects
HIV
HIV (Viruses)
HIV patients
Human immunodeficiency virus
Infectious Diseases
Internal Medicine
Medical treatment
Medicine
Medicine & Public Health
Pandemics
Prevention
Public health
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
South Africa
Vaccines
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Summary:The HIV pandemic has led to close to 40 million people living with HIV (PLWH) worldwide. To date, SARS-CoV2 has affected > 220 million people, and unprecedented global efforts have resulted in almost 6000 million doses of SARS-CoV2 vaccines being administered. Although several specific COVID-19 antiviral and anti-inflammatory treatments and SARS-CoV2 vaccines have been approved, the data available to support their use in specific populations such as PLWH remain limited. PLWH includes a range of individuals from practically unaffected immunity to severely immunocompromised individuals, and preventive and therapeutic interventions should be tailored for these subgroups . However, in most randomized clinical trials regarding antivirals, immunomodulators and vaccines for COVID-19, PLWH have been excluded or only enrolled in small numbers leading to a paucity of data. We briefly discuss the current evidence for prevention and treatment of COVID-19 in PLWH and identify key areas where more information is required.
ISSN:2193-8229
2193-6382
DOI:10.1007/s40121-021-00547-y