Nanotechnology-based products for cancer immunotherapy

Currently, nanoscale materials and scaffolds carrying antitumor agents to the tumor target site are practical approaches for cancer treatment. Immunotherapy is a modern approach to cancer treatment in which the body’s immune system adjusts to deal with cancer cells. Immuno-engineering is a new branc...

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Bibliographic Details
Published in:Molecular biology reports 2022-02, Vol.49 (2), p.1389-1412
Main Authors: Shams, Forough, Golchin, Ali, Azari, Arezo, Mohammadi Amirabad, Leila, Zarein, Fateme, Khosravi, Atiyeh, Ardeshirylajimi, Abdolreza
Format: Article
Language:English
Subjects:
Animal Anatomy
Animal Biochemistry
Animals
Antineoplastic Agents - therapeutic use
Antitumor agents
Biomedical and Life Sciences
Cancer
Cancer immunotherapy
Cancer therapies
Drug Delivery Systems - methods
Histology
Humans
Immune System
Immunologic Factors - therapeutic use
Immunotherapy
Immunotherapy - methods
Life Sciences
Morphology
Nanoparticles - administration & dosage
Nanotechnology
Nanotechnology - methods
Neoplasms - drug therapy
Neoplasms - immunology
Regenerative medicine
Review
Tumors
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Summary:Currently, nanoscale materials and scaffolds carrying antitumor agents to the tumor target site are practical approaches for cancer treatment. Immunotherapy is a modern approach to cancer treatment in which the body’s immune system adjusts to deal with cancer cells. Immuno-engineering is a new branch of regenerative medicine-based therapies that uses engineering principles by using biological tools to stimulate the immune system. Therefore, this branch’s final aim is to regulate distribution, release, and simultaneous placement of several immune factors at the tumor site, so then upgrade the current treatment methods and subsequently improve the immune system’s handling. In this paper, recent research and prospects of nanotechnology-based cancer immunotherapy have been presented and discussed. Furthermore, different encouraging nanotechnology-based plans for targeting various innate and adaptive immune systems will also be discussed. Due to novel views in nanotechnology strategies, this field can address some biological obstacles, although studies are ongoing. Graphic abstract
ISSN:0301-4851
1573-4978
DOI:10.1007/s11033-021-06876-y