Association of Myocardial Enzyme Abnormality with Clinical Outcomes of Patients with COVID-19: A Retrospective Study

Background. It has been observed that COVID-19 may cause myocardial damage, but there are few detailed reports on myocardial enzyme abnormalities. Methods. In this retrospective study, we analyzed data from 157 consecutive laboratory-confirmed and hospitalized COVID-19 patients from Wuhan. We collec...

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Bibliographic Details
Published in:Disease markers 2021, Vol.2021, p.3440714-9
Main Authors: Zhang, Qilin, Zheng, Ziming, Zhang, Yu
Format: Article
Language:English
Subjects:
Abnormalities
Adult
Alanine Transaminase - blood
Clinical outcomes
Coronaviruses
Correlation analysis
COVID-19
COVID-19 - blood
COVID-19 - enzymology
COVID-19 - mortality
Creatine Kinase, MB Form - blood
Cytokines
Dehydrogenases
Diabetes
Disease
Enzymes
Enzymes - blood
Female
Glucose
Heart
High density lipoprotein
Hospitals
Humans
Hypertension
Kinases
L-Lactate Dehydrogenase - blood
Laboratories
Logistic Models
Male
Medical records
Middle Aged
Mortality
Myocardium - enzymology
Patients
Regression analysis
Retrospective Studies
Risk analysis
Risk factors
Standard deviation
Statistical analysis
Troponin I - blood
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Summary:Background. It has been observed that COVID-19 may cause myocardial damage, but there are few detailed reports on myocardial enzyme abnormalities. Methods. In this retrospective study, we analyzed data from 157 consecutive laboratory-confirmed and hospitalized COVID-19 patients from Wuhan. We collected information on demographic and clinical characteristics, laboratory findings, and clinical outcomes. Logistic regression analysis was used to explore the risk factors associated with the severity of COVID-19. The association between myocardial enzyme abnormalities and the mortality was also investigated. Results. The mortality in abnormal myocardial enzyme group was obviously higher than the normal group (P
ISSN:0278-0240
1875-8630
DOI:10.1155/2021/3440714