The Dutch National TissueArchive Portal enables efficient, consistent, and transparent procurement of diagnostic tissue samples for scientific use

Biobanks play a crucial role in enabling biomedical research by facilitating scientific use of valuable human biomaterials. The PALGA foundation—a nationwide network and registry of histo- and cytopathology in the Netherlands—was established to promote the provision of data within and between pathol...

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Bibliographic Details
Published in:Cell and tissue banking 2021-12, Vol.22 (4), p.727-736
Main Authors: Verjans, Robin, Bruggink, Annette H., Kibbelaar, Robby, Bart, Jos, Debernardi, Aletta, Schaaij-Visser, Tieneke B. M., Willems, Stefan M., Van Kemenade, Folkert J.
Format: Article
Language:English
Subjects:
Biomaterials
Biomedical and Life Sciences
Biomedical Research
Biomedicine
Cell Biology
Cytopathology
Humans
Life Sciences
Medical diagnosis
Medical research
Netherlands
Paraffin
Pathology
Precision medicine
Transplant Surgery
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Summary:Biobanks play a crucial role in enabling biomedical research by facilitating scientific use of valuable human biomaterials. The PALGA foundation—a nationwide network and registry of histo- and cytopathology in the Netherlands—was established to promote the provision of data within and between pathology departments, and to make the resulting knowledge available for healthcare. Apart from the pathology data, we aimed to utilize PALGA’s nationwide network to find and access the rich wealth of Formalin-Fixed Paraffin-Embedded (FFPE) tissue samples for scientific use.  We implemented the Dutch National TissueArchive Portal (DNTP) to utilize PALGA’s nationwide network for requesting FFPE tissue samples. The DNTP consists of (1) a centrally organized internet portal to improve the assessing, processing, harmonization, and monitoring of the procurement process, while (2) dedicated HUB-employees provide practical support at peripheral pathology departments. Since incorporation of the DNTP, both the number of filed requests for FFPE tissue samples and the amount of HUB-mediated support increased 55 and 29% respectively. In line, the sample procurement duration time decreased significantly (− 47%). These findings indicate that implementation of the DNTP improved the frequency, efficiency, and transparency of FFPE tissue sample procurement for research in the Netherlands. To conclude, the need for biological resources is growing persistently to enable precision medicine. Here, we access PALGA’s national, pathology network by implementation of the DNTP to allow for efficient, consistent, and transparent exchange of FFPE tissue samples for research across the Netherlands.
ISSN:1389-9333
1573-6814
DOI:10.1007/s10561-021-09949-1