Loading…

Outcomes of chronic graft-versus-host disease following matched sibling donor versus umbilical cord blood transplant

We compared chronic graft-versus-host disease (cGvHD) following umbilical cord blood (UCBT) and matched sibling donor peripheral blood transplant (MSD). 145 patients (2010–2017) with cGvHD after MSD ( n  = 104) and UCBT ( n  = 41) were included. Prior acute GvHD was less frequent in MSD (55% vs. 85%...

Full description

Saved in:
Bibliographic Details
Published in:Bone marrow transplantation (Basingstoke) 2021-06, Vol.56 (6), p.1373-1380
Main Authors: Okoev, Grigori, Weisdorf, Daniel J., Wagner, John E., Blazar, Bruce R., MacMillan, Margaret L., DeFor, Todd, Lazaryan, Aleksandr, El Jurdi, Najla, Holtan, Shernan G., Brunstein, Claudio G., Betts, Brian C., Takahashi, Takuto, Bachanova, Veronika, Warlick, Erica D., Rashidi, Armin, Arora, Mukta
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We compared chronic graft-versus-host disease (cGvHD) following umbilical cord blood (UCBT) and matched sibling donor peripheral blood transplant (MSD). 145 patients (2010–2017) with cGvHD after MSD ( n  = 104) and UCBT ( n  = 41) were included. Prior acute GvHD was less frequent in MSD (55% vs. 85%; p  = 0.01). Severe cGvHD (32% vs. 15%, p  = 0.01) and de-novo onset (45% vs. 15%, p  
ISSN:0268-3369
1476-5365
DOI:10.1038/s41409-020-01195-5