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Outcomes of chronic graft-versus-host disease following matched sibling donor versus umbilical cord blood transplant
We compared chronic graft-versus-host disease (cGvHD) following umbilical cord blood (UCBT) and matched sibling donor peripheral blood transplant (MSD). 145 patients (2010–2017) with cGvHD after MSD ( n = 104) and UCBT ( n = 41) were included. Prior acute GvHD was less frequent in MSD (55% vs. 85%...
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Published in: | Bone marrow transplantation (Basingstoke) 2021-06, Vol.56 (6), p.1373-1380 |
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Main Authors: | , , , , , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | We compared chronic graft-versus-host disease (cGvHD) following umbilical cord blood (UCBT) and matched sibling donor peripheral blood transplant (MSD). 145 patients (2010–2017) with cGvHD after MSD (
n
= 104) and UCBT (
n
= 41) were included. Prior acute GvHD was less frequent in MSD (55% vs. 85%;
p
= 0.01). Severe cGvHD (32% vs. 15%,
p
= 0.01) and de-novo onset (45% vs. 15%,
p
|
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ISSN: | 0268-3369 1476-5365 |
DOI: | 10.1038/s41409-020-01195-5 |