Postloading insulinemia is independently associated with arterial stiffness in young Japanese persons

Associations of arterial stiffness with glucose, insulin, and proinsulin dynamics during the oral glucose tolerance test (OGTT) remain under debate. The aim of this study was to investigate whether plasma glucose (PG), insulin, and proinsulin (Pro) contribute to arterial stiffness, measured by pulse...

Full description

Saved in:
Bibliographic Details
Published in:Hypertension research 2021-11, Vol.44 (11), p.1515-1523
Main Authors: Murai, Norimitsu, Saito, Naoko, Nii, Sayuri, Nishikawa, Yuto, Suzuki, Asami, Kodama, Eriko, Iida, Tatsuya, Mikura, Kentaro, Imai, Hideyuki, Hashizume, Mai, Kigawa, Yasuyoshi, Tadokoro, Rie, Sugisawa, Chiho, Endo, Kei, Iizaka, Toru, Otsuka, Fumiko, Ishibashi, Shun, Nagasaka, Shoichiro
Format: Article
Language:English
Subjects:
Blood Glucose
Cardiovascular disease
Glucose
Humans
Hypertension
Insulin
Insulin Resistance
Japan
Male
Pulse Wave Analysis
Vascular Stiffness
Young adults
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Associations of arterial stiffness with glucose, insulin, and proinsulin dynamics during the oral glucose tolerance test (OGTT) remain under debate. The aim of this study was to investigate whether plasma glucose (PG), insulin, and proinsulin (Pro) contribute to arterial stiffness, measured by pulse wave velocity (PWV), in young Japanese persons. PG, immunoreactive insulin (IRI), and Pro levels were determined in 1193 young Japanese subjects (
ISSN:0916-9636
1348-4214
DOI:10.1038/s41440-021-00749-4