Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021

We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination...

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Bibliographic Details
Published in:Euro surveillance : bulletin européen sur les maladies transmissibles 2021-11, Vol.26 (44), p.1
Main Authors: de Gier, Brechje, Andeweg, Stijn, Backer, Jantien A, Hahné, Susan JM, van den Hof, Susan, de Melker, Hester E, Knol, Mirjam J
Format: Article
Language:English
Subjects:
COVID-19
COVID-19 vaccines
Disease transmission
Health surveillance
Immunization
Rapid Communication
Severe acute respiratory syndrome coronavirus 2
Studies
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Summary:We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46–75) and 40% (95% CI: 20–54), in addition to the direct protection of vaccination of contacts against infection.
ISSN:1560-7917
1025-496X
1560-7917
DOI:10.2807/1560-7917.ES.2021.26.44.2100977