Virucidal activity of nasal sprays against severe acute respiratory syndrome coronavirus-2

The highest viral loads of severe acute respiratory syndrome coronavirus-2 are detectable in the oral cavity, so a potential reduction of infectious virus by nasal and oral sprays could reduce transmission. Therefore, the inactivation capacity of nine nasal and oral sprays was evaluated according to...

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Bibliographic Details
Published in:The Journal of hospital infection 2022-02, Vol.120, p.9-13
Main Authors: Meister, T.L., Todt, D., Brüggemann, Y., Steinmann, J., Banava, S., Brill, F.H.H., Pfaender, S., Steinmann, E.
Format: Article
Language:English
Subjects:
Aged
COVID-19
Humans
Inactivation
Mouth
Mouthwashes
Nasal spray
Nasal Sprays
Nasopharynx
Oral cavity
Oral spray
Quantitative suspension test
SARS-CoV-2
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
Short Report
Transmission
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Summary:The highest viral loads of severe acute respiratory syndrome coronavirus-2 are detectable in the oral cavity, so a potential reduction of infectious virus by nasal and oral sprays could reduce transmission. Therefore, the inactivation capacity of nine nasal and oral sprays was evaluated according to EN 14476. One nasal spray based on sodium hypochlorite and one oral spray containing essential oils reduced viral titres by two to three orders of magnitude. Although clinical data are still sparse, nasal and oral sprays display a more convenient application for elderly people or those who are unable to rinse/gargle.
ISSN:0195-6701
1532-2939
DOI:10.1016/j.jhin.2021.10.019