Aptameric nanobiosensors for the diagnosis of COVID-19: An update

[Display omitted] •Aptameric nanobiosensors is an affinity-based nanosensors interfaced with aptamers.•It is a rapid and sensitive diagnostic platform for the detection of SARS-CoV-2.•Detection limit of these apta-nanobiosensors vary from pM to fM concentrations.•Careful selection of aptamers and si...

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Bibliographic Details
Published in:Materials letters 2022-02, Vol.308, p.131237-131237, Article 131237
Main Authors: Krishnan, Saravanan, Kumar Narasimhan, Ashwin, Gangodkar, Durgaprasad, Dhanasekaran, Sugapriya, Kumar Jha, Niraj, Dua, Kamal, Thakur, Vijay Kumar, Kumar Gupta, Piyush
Format: Article
Language:English
Subjects:
Aptamers
Coronaviruses
COVID-19
Diagnosis
Disease transmission
Global economy
Materials science
Nanobiosensors
SARS-CoV-2
Sensitivity analysis
Severe acute respiratory syndrome coronavirus 2
Viral diseases
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Summary:[Display omitted] •Aptameric nanobiosensors is an affinity-based nanosensors interfaced with aptamers.•It is a rapid and sensitive diagnostic platform for the detection of SARS-CoV-2.•Detection limit of these apta-nanobiosensors vary from pM to fM concentrations.•Careful selection of aptamers and signal transducers is critical for better results. COVID-19 pandemic has left a catastrophic effect on the world economy and human civilization. As an effective step towards controlling the transmission of viral infections during multiple waves of COVID-19, there is an urgent need to develop robust nanobiosensors for the detection of SARS-CoV-2 with high sensitivity, specificity, and fast analysis. Aptameric nanobiosensors are rapid and sensitive diagnostic platforms, capable of SARS-CoV-2 detection, which overcomes the limitations of the conventional techniques. This review article presents an outline of the aptameric nanobiosensors established for improved diagnosis of SARS-CoV-2 and the future perspectives are also covered.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2021.131237