Detection of fluconazole-resistant Candida strains by a disc diffusion screening test

A commercial disc diffusion test has been evaluated as a screening method for the detection of Candida species with decreased susceptibility to fluconazole. A total of 1,407 Candida strains of different species were tested, and the results were compared with the MIC results. The recently published N...

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Bibliographic Details
Published in:Journal of clinical microbiology 1999-12, Vol.37 (12), p.3856-3859
Main Author: SANDVEN, P
Format: Article
Language:English
Subjects:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Antifungal Agents - pharmacology
Biological and medical sciences
Candida
Candida - drug effects
Candida albicans - drug effects
Candidiasis - microbiology
Diffusion
Drug Resistance, Microbial
Fluconazole - pharmacology
Humans
Medical sciences
Microbial Sensitivity Tests - methods
Mycology
Pharmacology. Drug treatments
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Summary:A commercial disc diffusion test has been evaluated as a screening method for the detection of Candida species with decreased susceptibility to fluconazole. A total of 1,407 Candida strains of different species were tested, and the results were compared with the MIC results. The recently published National Committee for Clinical Laboratory Standards breakpoint criteria have been used. Isolates were classified as susceptible if the MIC for the isolates was /=64 microg/ml. All 77 resistant strains and 121 of 122 S-DD strains had fluconazole zone diameters of
ISSN:0095-1137
1098-660X
DOI:10.1128/jcm.37.12.3856-3859.1999