Corynebacterium freneyi as a cause of early prosthetic valve endocarditis

Infective endocarditis (IE) is associated with severe complications and a high mortality rate. Identification of the causative pathogen is crucial to optimise treatment. We present a case of prosthetic valve endocarditis caused by , a very rare cause of human infection and not previously reported as...

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Bibliographic Details
Published in:BMJ case reports 2021-11, Vol.14 (11), p.e245152
Main Authors: Grenne, Bjørnar, Dalen, Håvard, Nordhaug, Dag Ole, Sand-Aas, Torgeir, Holte, Espen, Damås, Jan Kristian, Mjølstad, Ole Christian
Format: Article
Language:English
Subjects:
Antibiotics
Blood
Case Report
Case reports
Corynebacterium
Endocarditis
Endocarditis, Bacterial - diagnosis
Endocarditis, Bacterial - drug therapy
Fever
Gram-positive bacteria
Heart Valve Prosthesis - adverse effects
Hospitals
Humans
Infections
Male
Pacemakers
Prostheses
Prosthesis-Related Infections - diagnosis
Prosthesis-Related Infections - drug therapy
Thoracic surgery
Vegetation
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Summary:Infective endocarditis (IE) is associated with severe complications and a high mortality rate. Identification of the causative pathogen is crucial to optimise treatment. We present a case of prosthetic valve endocarditis caused by , a very rare cause of human infection and not previously reported as a cause of IE. Despite proper antibiotic therapy, the patient eventually needed surgery after progression of the infection. After surgery, he quickly recovered without evidence of relapse during an 8-month follow-up period. This report highlights critical decision making in a complex and potentially life-threatening situation, where neither guidelines nor previous clinical or microbiological experience were able to give clear treatment recommendations.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2021-245152