Effect of Traditional Chinese Medicine Combined with Bladder Perfusion with Hydroxycamptothecin on Color Ultrasound and Clinical Efficacy in Patients with Bladder Cancer Surgery

Objective. To observe the clinical effect of Xiaozheng Decoction combined with bladder perfusion with hydroxycamptothecin in the treatment of bladder cancer. Methods. A total of 92 bladder cancer patients admitted to our hospital from January to December 2018 were selected and divided into an observ...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2021, Vol.2021, p.7178414-8
Main Authors: Zhou, Shisheng, Fan, Xia, Du, Xiaojie, Liu, Shuang, Sun, Hongmei, Zhang, Yan
Format: Article
Language:English
Subjects:
Bladder cancer
Blood
Cancer
Cancer surgery
Cancer therapies
CD3 antigen
CD4 antigen
CD8 antigen
Cell adhesion molecules
Chemotherapy
Chinese medicine
Color
Drugs
E-cadherin
Fibroblast growth factors
Flow cytometry
Hematuria
Hospitals
Immune response
Intercellular adhesion molecule 1
Medical diagnosis
Methods
Patients
Perfusion
Quality of life
Side effects
Statistical analysis
Surgery
Traditional Chinese medicine
Ultrasonic imaging
Ultrasound
Urination
Urology
Vascular endothelial growth factor
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Summary:Objective. To observe the clinical effect of Xiaozheng Decoction combined with bladder perfusion with hydroxycamptothecin in the treatment of bladder cancer. Methods. A total of 92 bladder cancer patients admitted to our hospital from January to December 2018 were selected and divided into an observation group and a control group according to the random number table method, with 46 cases in each group. The observation group was given Xiaozheng Decoction combined with bladder perfusion with hydroxycamptothecin, and the control group was given hydroxycamptothecin. The levels of serum-related factors (intercellular adhesion molecule-1 (ICAM-1), E-cadherin, cell adhesion molecules (CAM), fibroblast growth factor (FGF), and vascular endothelial growth factor (VEGF)), white blood cell (WBC) level, immune function indexes, short-term total response rate, and incidence of adverse reactions were compared between the two groups before and after treatment. Results. After 2 years of postoperative treatment, the levels of ICAM-1, E-cadherin, CAM-1, FGF, and VEGF (a, b, c) in both groups were improved compared with those before treatment and the observation group was better than the control group p
ISSN:1741-427X
1741-4288
DOI:10.1155/2021/7178414