Development of a Purified Viral Preparation for Studies of COVID-19 (SARS-CoV-2) Biology

Different methods for producing bulk quantities of concentrated and purified SARS-CoV-2 for the use as antigens and for the research into COVID-19 biology were tested.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2021-11, Vol.172 (1), p.49-52
Main Authors: Chepurnov, A. A., Kazachinskaya, E. I., Kazachkova, E. A., Sharshov, K. A., Kononova, Yu. V., Shelemba, A. A., Alekseev, A. Yu, Gulyeva, M. A., Voevoda, M. I., Shestopalov, A. M.
Format: Article
Language:English
Subjects:
Animals
Antibodies
Antibodies, Neutralizing - isolation & purification
Antibodies, Neutralizing - metabolism
Antibodies, Viral - isolation & purification
Antibodies, Viral - metabolism
Antigens
Biomedical and Life Sciences
Biomedicine
Cell Biology
Cell Line
Chlorocebus aethiops
Convalescence
Coronaviruses
COVID-19
COVID-19 - diagnosis
COVID-19 - virology
COVID-19 Testing - methods
Epithelial Cells - virology
Health aspects
Humans
Immune Sera - chemistry
Internal Medicine
Laboratory Medicine
Pathology
Proteins
SARS-CoV-2 - genetics
SARS-CoV-2 - growth & development
SARS-CoV-2 - immunology
Severe acute respiratory syndrome coronavirus 2
Swine
Vaccines
Vero Cells
Viral antibodies
Viral Load - genetics
Viral Load - immunology
Viral Proteins - immunology
Viral Proteins - isolation & purification
Viral Proteins - metabolism
Virion - genetics
Virion - growth & development
Virion - immunology
Virology
Virus Replication
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Description
Summary:Different methods for producing bulk quantities of concentrated and purified SARS-CoV-2 for the use as antigens and for the research into COVID-19 biology were tested.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-021-05329-7