Loading…

Direct and Indirect Costs of Non-surgical Treatment for Acute Tonsillitis in Children in Southeast Nigeria

Background Acute tonsillitis has become one of the main reasons why children visit healthcare facilities in Nigeria. Presently, there is no information on the costs of its treatment, and this study aimed at determining these costs. Methods The study was conducted in two hospitals located in southeas...

Full description

Saved in:
Bibliographic Details
Published in:PharmacoEconomics - open 2021-12, Vol.5 (4), p.755-764
Main Authors: Ughasoro, Maduka Donatus, Akpeh, James Onuorah, Echendu, Nneamaka, Okpala, Somkene, Mgbachi, Nneka Getrude, Okanya, Ogochukwu Chinelo, Onwujekwe, Obinna Emmanuel
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c541t-e6980514601d4c9303a185b192d473dd6493eae3ce8038e3ce6665902307e77b3
cites cdi_FETCH-LOGICAL-c541t-e6980514601d4c9303a185b192d473dd6493eae3ce8038e3ce6665902307e77b3
container_end_page 764
container_issue 4
container_start_page 755
container_title PharmacoEconomics - open
container_volume 5
creator Ughasoro, Maduka Donatus
Akpeh, James Onuorah
Echendu, Nneamaka
Okpala, Somkene
Mgbachi, Nneka Getrude
Okanya, Ogochukwu Chinelo
Onwujekwe, Obinna Emmanuel
description Background Acute tonsillitis has become one of the main reasons why children visit healthcare facilities in Nigeria. Presently, there is no information on the costs of its treatment, and this study aimed at determining these costs. Methods The study was conducted in two hospitals located in southeast Nigeria. The information was obtained in two ways: (1) retrospectively from the medical records of children treated for acute tonsillitis over a period of 5 years and (2) cross-sectionally from children who presented with complaints of acute tonsillitis over a period of 7 months. The information obtained was the costs of self-medication and hospital treatment, and the payment mechanisms used to settle these costs. The human capital method approach was used to estimate the indirect cost (loss in productivity) from the caregivers’ absenteeism from work. Results The mean costs of self-medication and hospital treatment for acute tonsillitis in children were €3.85 and €13.48, respectively. The indirect cost was €11.31. The mean total cost of treatment of acute tonsillitis was €23.80. The proportion of households that suffered catastrophic health expenditure (CHE) from the treatment of acute tonsillitis was 55 (55%). CHE was highest [22 (91.7%)] in the lowest socio-economic quartile compared to households in the highest quartile [4 (16.7%)], and the difference was statistically significant ( p  = 0.02). Of the 72 participants whose payment mechanisms were documented, the proportion who paid out of pocket was 53 (73.6%), and 19 (26.4%) used the National Health Insurance Scheme. Conclusion The costs of treatment for children with acute tonsillitis were high, and most of these costs were settled out-of-pocket. The costs for laboratory investigations, drugs, and productivity loss contributed to these high costs. There is a need to cover the costs of non-surgical treatment of acute tonsillitis in social health insurance and improve efforts to increase the coverage of the health insurance scheme.
doi_str_mv 10.1007/s41669-021-00259-6
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8611136</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2510255395</sourcerecordid><originalsourceid>FETCH-LOGICAL-c541t-e6980514601d4c9303a185b192d473dd6493eae3ce8038e3ce6665902307e77b3</originalsourceid><addsrcrecordid>eNp9kctuEzEUhkeIilZtX4AFssSGzYCP794gVaFApaosCGvL8TiJo4ldbE8l3r4OU8Jlweoc63z-z-XvupeA3wLG8l1hIITuMYEeY8J1L551Z4Rj3TPC2fNjLshpd1nKDmMMSoGU8KI7pVRRzJQ863YfQvauIhsHdBOH-bFIpRaU1uguxb5MeROcHdEye1v3Pla0Thldual6tEyxhHEMNRQUIlpswzhkHw_51zTVrbeloruw8TnYi-5kbcfiL5_iefft4_Vy8bm__fLpZnF12zvOoPZeaIU5MIFhYE5TTC0ovgJNBibpMAimqbeeOq8wVYcohOAaE4qll3JFz7v3s-79tNr7wbWJsx3NfQ57m3-YZIP5uxLD1mzSg1ECAKhoAm-eBHL6PvlSzT4U58fRRp-mYgiHdnFONW_o63_QXZpybOsZIkkDKAHWKDJTLqdSsl8fhwFsDm6a2U3T3DQ_3TSHKV79ucbxyy_vGkBnoLRSbCf-3fs_so_uX6ob</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2729533214</pqid></control><display><type>article</type><title>Direct and Indirect Costs of Non-surgical Treatment for Acute Tonsillitis in Children in Southeast Nigeria</title><source>Publicly Available Content Database</source><source>ABI/INFORM Global</source><source>Springer Nature - SpringerLink Journals - Fully Open Access </source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Ughasoro, Maduka Donatus ; Akpeh, James Onuorah ; Echendu, Nneamaka ; Okpala, Somkene ; Mgbachi, Nneka Getrude ; Okanya, Ogochukwu Chinelo ; Onwujekwe, Obinna Emmanuel</creator><creatorcontrib>Ughasoro, Maduka Donatus ; Akpeh, James Onuorah ; Echendu, Nneamaka ; Okpala, Somkene ; Mgbachi, Nneka Getrude ; Okanya, Ogochukwu Chinelo ; Onwujekwe, Obinna Emmanuel</creatorcontrib><description>Background Acute tonsillitis has become one of the main reasons why children visit healthcare facilities in Nigeria. Presently, there is no information on the costs of its treatment, and this study aimed at determining these costs. Methods The study was conducted in two hospitals located in southeast Nigeria. The information was obtained in two ways: (1) retrospectively from the medical records of children treated for acute tonsillitis over a period of 5 years and (2) cross-sectionally from children who presented with complaints of acute tonsillitis over a period of 7 months. The information obtained was the costs of self-medication and hospital treatment, and the payment mechanisms used to settle these costs. The human capital method approach was used to estimate the indirect cost (loss in productivity) from the caregivers’ absenteeism from work. Results The mean costs of self-medication and hospital treatment for acute tonsillitis in children were €3.85 and €13.48, respectively. The indirect cost was €11.31. The mean total cost of treatment of acute tonsillitis was €23.80. The proportion of households that suffered catastrophic health expenditure (CHE) from the treatment of acute tonsillitis was 55 (55%). CHE was highest [22 (91.7%)] in the lowest socio-economic quartile compared to households in the highest quartile [4 (16.7%)], and the difference was statistically significant ( p  = 0.02). Of the 72 participants whose payment mechanisms were documented, the proportion who paid out of pocket was 53 (73.6%), and 19 (26.4%) used the National Health Insurance Scheme. Conclusion The costs of treatment for children with acute tonsillitis were high, and most of these costs were settled out-of-pocket. The costs for laboratory investigations, drugs, and productivity loss contributed to these high costs. There is a need to cover the costs of non-surgical treatment of acute tonsillitis in social health insurance and improve efforts to increase the coverage of the health insurance scheme.</description><identifier>ISSN: 2509-4262</identifier><identifier>ISSN: 2509-4254</identifier><identifier>EISSN: 2509-4254</identifier><identifier>DOI: 10.1007/s41669-021-00259-6</identifier><identifier>PMID: 33830487</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Antibiotics ; Caregivers ; Developing countries ; Health care expenditures ; Health insurance ; Hospitals ; Households ; Industrialized nations ; Laboratories ; LDCs ; Medical records ; Medicine ; Medicine &amp; Public Health ; Original ; Original Research Article ; Patients ; Pediatrics ; Pharmacoeconomics and Health Outcomes ; Population ; Rural areas ; Self-medication ; State budgets ; Throat surgery ; Tonsillitis</subject><ispartof>PharmacoEconomics - open, 2021-12, Vol.5 (4), p.755-764</ispartof><rights>The Author(s) 2021</rights><rights>2021. The Author(s).</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c541t-e6980514601d4c9303a185b192d473dd6493eae3ce8038e3ce6665902307e77b3</citedby><cites>FETCH-LOGICAL-c541t-e6980514601d4c9303a185b192d473dd6493eae3ce8038e3ce6665902307e77b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2729533214/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2729533214?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,11687,25752,27923,27924,36059,36060,37011,37012,44362,44589,53790,53792,74666,74897</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33830487$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ughasoro, Maduka Donatus</creatorcontrib><creatorcontrib>Akpeh, James Onuorah</creatorcontrib><creatorcontrib>Echendu, Nneamaka</creatorcontrib><creatorcontrib>Okpala, Somkene</creatorcontrib><creatorcontrib>Mgbachi, Nneka Getrude</creatorcontrib><creatorcontrib>Okanya, Ogochukwu Chinelo</creatorcontrib><creatorcontrib>Onwujekwe, Obinna Emmanuel</creatorcontrib><title>Direct and Indirect Costs of Non-surgical Treatment for Acute Tonsillitis in Children in Southeast Nigeria</title><title>PharmacoEconomics - open</title><addtitle>PharmacoEconomics Open</addtitle><addtitle>Pharmacoecon Open</addtitle><description>Background Acute tonsillitis has become one of the main reasons why children visit healthcare facilities in Nigeria. Presently, there is no information on the costs of its treatment, and this study aimed at determining these costs. Methods The study was conducted in two hospitals located in southeast Nigeria. The information was obtained in two ways: (1) retrospectively from the medical records of children treated for acute tonsillitis over a period of 5 years and (2) cross-sectionally from children who presented with complaints of acute tonsillitis over a period of 7 months. The information obtained was the costs of self-medication and hospital treatment, and the payment mechanisms used to settle these costs. The human capital method approach was used to estimate the indirect cost (loss in productivity) from the caregivers’ absenteeism from work. Results The mean costs of self-medication and hospital treatment for acute tonsillitis in children were €3.85 and €13.48, respectively. The indirect cost was €11.31. The mean total cost of treatment of acute tonsillitis was €23.80. The proportion of households that suffered catastrophic health expenditure (CHE) from the treatment of acute tonsillitis was 55 (55%). CHE was highest [22 (91.7%)] in the lowest socio-economic quartile compared to households in the highest quartile [4 (16.7%)], and the difference was statistically significant ( p  = 0.02). Of the 72 participants whose payment mechanisms were documented, the proportion who paid out of pocket was 53 (73.6%), and 19 (26.4%) used the National Health Insurance Scheme. Conclusion The costs of treatment for children with acute tonsillitis were high, and most of these costs were settled out-of-pocket. The costs for laboratory investigations, drugs, and productivity loss contributed to these high costs. There is a need to cover the costs of non-surgical treatment of acute tonsillitis in social health insurance and improve efforts to increase the coverage of the health insurance scheme.</description><subject>Antibiotics</subject><subject>Caregivers</subject><subject>Developing countries</subject><subject>Health care expenditures</subject><subject>Health insurance</subject><subject>Hospitals</subject><subject>Households</subject><subject>Industrialized nations</subject><subject>Laboratories</subject><subject>LDCs</subject><subject>Medical records</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Original</subject><subject>Original Research Article</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Pharmacoeconomics and Health Outcomes</subject><subject>Population</subject><subject>Rural areas</subject><subject>Self-medication</subject><subject>State budgets</subject><subject>Throat surgery</subject><subject>Tonsillitis</subject><issn>2509-4262</issn><issn>2509-4254</issn><issn>2509-4254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>M0C</sourceid><sourceid>PIMPY</sourceid><recordid>eNp9kctuEzEUhkeIilZtX4AFssSGzYCP794gVaFApaosCGvL8TiJo4ldbE8l3r4OU8Jlweoc63z-z-XvupeA3wLG8l1hIITuMYEeY8J1L551Z4Rj3TPC2fNjLshpd1nKDmMMSoGU8KI7pVRRzJQ863YfQvauIhsHdBOH-bFIpRaU1uguxb5MeROcHdEye1v3Pla0Thldual6tEyxhHEMNRQUIlpswzhkHw_51zTVrbeloruw8TnYi-5kbcfiL5_iefft4_Vy8bm__fLpZnF12zvOoPZeaIU5MIFhYE5TTC0ovgJNBibpMAimqbeeOq8wVYcohOAaE4qll3JFz7v3s-79tNr7wbWJsx3NfQ57m3-YZIP5uxLD1mzSg1ECAKhoAm-eBHL6PvlSzT4U58fRRp-mYgiHdnFONW_o63_QXZpybOsZIkkDKAHWKDJTLqdSsl8fhwFsDm6a2U3T3DQ_3TSHKV79ucbxyy_vGkBnoLRSbCf-3fs_so_uX6ob</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Ughasoro, Maduka Donatus</creator><creator>Akpeh, James Onuorah</creator><creator>Echendu, Nneamaka</creator><creator>Okpala, Somkene</creator><creator>Mgbachi, Nneka Getrude</creator><creator>Okanya, Ogochukwu Chinelo</creator><creator>Onwujekwe, Obinna Emmanuel</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88C</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M0T</scope><scope>PIMPY</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20211201</creationdate><title>Direct and Indirect Costs of Non-surgical Treatment for Acute Tonsillitis in Children in Southeast Nigeria</title><author>Ughasoro, Maduka Donatus ; Akpeh, James Onuorah ; Echendu, Nneamaka ; Okpala, Somkene ; Mgbachi, Nneka Getrude ; Okanya, Ogochukwu Chinelo ; Onwujekwe, Obinna Emmanuel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c541t-e6980514601d4c9303a185b192d473dd6493eae3ce8038e3ce6665902307e77b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Antibiotics</topic><topic>Caregivers</topic><topic>Developing countries</topic><topic>Health care expenditures</topic><topic>Health insurance</topic><topic>Hospitals</topic><topic>Households</topic><topic>Industrialized nations</topic><topic>Laboratories</topic><topic>LDCs</topic><topic>Medical records</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Original</topic><topic>Original Research Article</topic><topic>Patients</topic><topic>Pediatrics</topic><topic>Pharmacoeconomics and Health Outcomes</topic><topic>Population</topic><topic>Rural areas</topic><topic>Self-medication</topic><topic>State budgets</topic><topic>Throat surgery</topic><topic>Tonsillitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ughasoro, Maduka Donatus</creatorcontrib><creatorcontrib>Akpeh, James Onuorah</creatorcontrib><creatorcontrib>Echendu, Nneamaka</creatorcontrib><creatorcontrib>Okpala, Somkene</creatorcontrib><creatorcontrib>Mgbachi, Nneka Getrude</creatorcontrib><creatorcontrib>Okanya, Ogochukwu Chinelo</creatorcontrib><creatorcontrib>Onwujekwe, Obinna Emmanuel</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest_ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>ProQuest_Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Global</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest Healthcare Administration Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>PharmacoEconomics - open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ughasoro, Maduka Donatus</au><au>Akpeh, James Onuorah</au><au>Echendu, Nneamaka</au><au>Okpala, Somkene</au><au>Mgbachi, Nneka Getrude</au><au>Okanya, Ogochukwu Chinelo</au><au>Onwujekwe, Obinna Emmanuel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Direct and Indirect Costs of Non-surgical Treatment for Acute Tonsillitis in Children in Southeast Nigeria</atitle><jtitle>PharmacoEconomics - open</jtitle><stitle>PharmacoEconomics Open</stitle><addtitle>Pharmacoecon Open</addtitle><date>2021-12-01</date><risdate>2021</risdate><volume>5</volume><issue>4</issue><spage>755</spage><epage>764</epage><pages>755-764</pages><issn>2509-4262</issn><issn>2509-4254</issn><eissn>2509-4254</eissn><abstract>Background Acute tonsillitis has become one of the main reasons why children visit healthcare facilities in Nigeria. Presently, there is no information on the costs of its treatment, and this study aimed at determining these costs. Methods The study was conducted in two hospitals located in southeast Nigeria. The information was obtained in two ways: (1) retrospectively from the medical records of children treated for acute tonsillitis over a period of 5 years and (2) cross-sectionally from children who presented with complaints of acute tonsillitis over a period of 7 months. The information obtained was the costs of self-medication and hospital treatment, and the payment mechanisms used to settle these costs. The human capital method approach was used to estimate the indirect cost (loss in productivity) from the caregivers’ absenteeism from work. Results The mean costs of self-medication and hospital treatment for acute tonsillitis in children were €3.85 and €13.48, respectively. The indirect cost was €11.31. The mean total cost of treatment of acute tonsillitis was €23.80. The proportion of households that suffered catastrophic health expenditure (CHE) from the treatment of acute tonsillitis was 55 (55%). CHE was highest [22 (91.7%)] in the lowest socio-economic quartile compared to households in the highest quartile [4 (16.7%)], and the difference was statistically significant ( p  = 0.02). Of the 72 participants whose payment mechanisms were documented, the proportion who paid out of pocket was 53 (73.6%), and 19 (26.4%) used the National Health Insurance Scheme. Conclusion The costs of treatment for children with acute tonsillitis were high, and most of these costs were settled out-of-pocket. The costs for laboratory investigations, drugs, and productivity loss contributed to these high costs. There is a need to cover the costs of non-surgical treatment of acute tonsillitis in social health insurance and improve efforts to increase the coverage of the health insurance scheme.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>33830487</pmid><doi>10.1007/s41669-021-00259-6</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2509-4262
ispartof PharmacoEconomics - open, 2021-12, Vol.5 (4), p.755-764
issn 2509-4262
2509-4254
2509-4254
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8611136
source Publicly Available Content Database; ABI/INFORM Global; Springer Nature - SpringerLink Journals - Fully Open Access ; PubMed Central; Alma/SFX Local Collection
subjects Antibiotics
Caregivers
Developing countries
Health care expenditures
Health insurance
Hospitals
Households
Industrialized nations
Laboratories
LDCs
Medical records
Medicine
Medicine & Public Health
Original
Original Research Article
Patients
Pediatrics
Pharmacoeconomics and Health Outcomes
Population
Rural areas
Self-medication
State budgets
Throat surgery
Tonsillitis
title Direct and Indirect Costs of Non-surgical Treatment for Acute Tonsillitis in Children in Southeast Nigeria
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T07%3A02%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Direct%20and%20Indirect%20Costs%20of%20Non-surgical%20Treatment%20for%20Acute%20Tonsillitis%20in%20Children%20in%20Southeast%20Nigeria&rft.jtitle=PharmacoEconomics%20-%20open&rft.au=Ughasoro,%20Maduka%20Donatus&rft.date=2021-12-01&rft.volume=5&rft.issue=4&rft.spage=755&rft.epage=764&rft.pages=755-764&rft.issn=2509-4262&rft.eissn=2509-4254&rft_id=info:doi/10.1007/s41669-021-00259-6&rft_dat=%3Cproquest_pubme%3E2510255395%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c541t-e6980514601d4c9303a185b192d473dd6493eae3ce8038e3ce6665902307e77b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2729533214&rft_id=info:pmid/33830487&rfr_iscdi=true