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Enterovirus D68-Associated Acute Respiratory Illness — New Vaccine Surveillance Network, United States, July–November 2018–2020

Enterovirus D68 (EV-D68) is associated with a broad spectrum of illnesses, including mild to severe acute respiratory illness (ARI) and acute flaccid myelitis (AFM). Enteroviruses, including EV-D68, are typically detected in the United States during late summer through fall, with year-to-year fluctu...

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Published in:MMWR. Morbidity and mortality weekly report 2021-11, Vol.70 (47), p.1623-1628
Main Authors: Shah, Melisa M., Perez, Ariana, Lively, Joana Y., Avadhanula, Vasanthi, Boom, Julie A., Chappell, James, Englund, Janet A., Fregoe, Wende, Halasa, Natasha B., Harrison, Christopher J., Hickey, Robert W., Klein, Eileen J., McNeal, Monica M., Michaels, Marian G., Moffatt, Mary E., Otten, Catherine, Sahni, Leila C., Schlaudecker, Elizabeth, Schuster, Jennifer E., Selvarangan, Rangaraj, Staat, Mary A., Stewart, Laura S., Weinberg, Geoffrey A., Williams, John V., Ng, Terry Fan Fei, Routh, Janell A., Gerber, Susan I., McMorrow, Meredith L., Rha, Brian, Midgley, Claire M.
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Language:English
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Summary:Enterovirus D68 (EV-D68) is associated with a broad spectrum of illnesses, including mild to severe acute respiratory illness (ARI) and acute flaccid myelitis (AFM). Enteroviruses, including EV-D68, are typically detected in the United States during late summer through fall, with year-to-year fluctuations. Before 2014, EV-D68 was infrequently reported to CDC (1). However, numbers of EV-D68 detection have increased in recent years, with a biennial pattern observed during 2014-2018 in the United States, after the expansion of surveillance and wider availability of molecular testing. In 2014, a national outbreak of EV-D68 was detected (2). EV-D68 was also reported in 2016 via local (3) and passive national (4) surveillance. EV-D68 detections were limited in 2017, but substantial circulation was observed in 2018 (5). To assess recent levels of circulation, EV-D68 detections in respiratory specimens collected from patients aged
ISSN:0149-2195
1545-861X
DOI:10.15585/MMWR.MM7047A1