Low eGFR Is a Strong Predictor of Worse Outcome in Hospitalized COVID-19 Patients

Background: The clinical course of COVID-19 is more severe in elderly patients with cardio-metabolic co-morbidities. Chronic kidney disease is considered an independent cardiovascular risk factor. We aimed to evaluate the impact of reduced eGFR on the composite outcome of admission to ICU and death...

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Published in:Journal of clinical medicine 2021-11, Vol.10 (22), p.5224
Main Authors: Mirijello, Antonio, Piscitelli, Pamela, de Matthaeis, Angela, Inglese, Michele, D’Errico, Maria Maddalena, Massa, Valentina, Greco, Antonio, Fontana, Andrea, Copetti, Massimiliano, Florio, Lucia, Leone, Maurizio Angelo, Prencipe, Michele Antonio, Aucella, Filippo, De Cosmo, Salvatore
Format: Article
Language:English
Subjects:
Age
Chronic illnesses
Clinical deterioration
Clinical medicine
Consent
Coronaviruses
COVID-19
Creatinine
Dementia
Diabetes
Epidemiology
Hypertension
Infections
Kidney diseases
Metabolism
Severe acute respiratory syndrome coronavirus 2
Statistical analysis
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Summary:Background: The clinical course of COVID-19 is more severe in elderly patients with cardio-metabolic co-morbidities. Chronic kidney disease is considered an independent cardiovascular risk factor. We aimed to evaluate the impact of reduced eGFR on the composite outcome of admission to ICU and death in a sample of consecutive COVID-19 hospitalized patients. Methods: We retrospectively evaluated clinical records of a consecutive sample of hospitalized COVID-19 patients. A total of 231 patients were considered for statistical analysis. The whole sample was divided in two groups on the basis of eGFR value, e.g., ≥ or
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm10225224