Healing of colonic anastomosis in rats under obstructive ileus conditions

BACKGROUNDThe anastomosis leak in colon resections is a crucial post-operative complication with significant morbidity and mortality. Methods: Forty (40) Wistar rats were allocated in two groups. In SHAM group only anastomosis was performed. In ILEUS group anastomosis was performed following one day...

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Published in:Discoveries (Craiova, Romania) Romania), 2021-06, Vol.9 (2), p.e129-e129
Main Authors: Despoudi, Kalliopi, Mantzoros, Ioannis, Ioannidis, Orestis, Loutzidou, Lydia, Christidis, Panagiotis, Chatzakis, Christos, Gkasdaris, Grigorios, Raptis, Dimitrios, Pramateftakis, Manousos George, Angelopoulos, Stamatios, Zaraboukas, Thomas, Koliakos, George, Tsalis, Konstantinos
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Language:English
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Summary:BACKGROUNDThe anastomosis leak in colon resections is a crucial post-operative complication with significant morbidity and mortality. Methods: Forty (40) Wistar rats were allocated in two groups. In SHAM group only anastomosis was performed. In ILEUS group anastomosis was performed following one day of ileus. Animals in both groups were subdivided in two groups according to the day they were sacrificed, 4th or 8th post-operative day. A number of variables between the groups were estimated. RESULTSBody weight loss was higher following obstructive ileus on both days. Adhesion score in 4th and 8th post-operative day was higher in ILEUS1, ILEUS2 groups compared to SHAM1, SHAM2 groups respectively (p
ISSN:2359-7232
2359-7232
DOI:10.15190/d.2021.8