The role of protein oxidation in the development of diabetic microvascular complications

The role of protein oxidation in the development of diabetic microvascular complications was investigated. In total, 266 participants were split into five groups: Group 1; diabetes mellitus for at least 10 years without any complications, Group 2; diabetic nephropathy, Group 3; diabetic neuropathy,...

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Bibliographic Details
Published in:Northern Clinics of Istanbul 2021-01, Vol.8 (5), p.500-506
Main Authors: Mertoglu, Cuma, Siranli, Gulsah, Coban, T Abdulkadir, Karakurt, Yucel, Ersoy, Alevtina, Ozcicek, Adalet, Arslan, Yusuf, Gok, Gamze, Erel, Ozcan
Format: Article
Language:English
Subjects:
Diabetes
Diabetic nephropathy
Diabetic neuropathy
Diabetic retinopathy
Homeostasis
Ischemia
Original
Oxidation
Proteins
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Summary:The role of protein oxidation in the development of diabetic microvascular complications was investigated. In total, 266 participants were split into five groups: Group 1; diabetes mellitus for at least 10 years without any complications, Group 2; diabetic nephropathy, Group 3; diabetic neuropathy, Group 4; diabetic retinopathy, and Group 5; control group. Thiol, disulfide, ferroxidase, and ischemia-modified albumin (IMA) levels were analyzed in the serum. Native thiol, total thiol, and native thiol/total thiol were lower in Group 4 than Groups 1, 3, and 5 (p
ISSN:2148-4902
2536-4553
DOI:10.14744/nci.2021.33341