In-hospital outcomes of self-expanding and balloon-expandable transcatheter heart valves in Germany

Introduction The effect of valve type on outcomes in transfemoral transcatheter aortic valve replacement (TF-TAVR) has recently been subject of debate. We investigate outcomes of patients treated with balloon-expanding (BE) vs. self-expanding (SE) valves in in a cohort of all these procedures perfor...

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Bibliographic Details
Published in:Clinical research in cardiology 2021-12, Vol.110 (12), p.1977-1982
Main Authors: Stachon, Peter, Hehn, Philip, Wolf, Dennis, Heidt, Timo, Oettinger, Vera, Zehender, Manfred, Bode, Christoph, von zur Mühlen, Constantin, Kaier, Klaus
Format: Article
Language:English
Subjects:
Aged, 80 and over
Aorta
Aortic valve
Aortic Valve - surgery
Aortic Valve Stenosis - surgery
Balloon treatment
Bleeding
Cardiology
Complications
Delirium
Female
Follow-Up Studies
Germany - epidemiology
Heart Valve Prosthesis
Heart valves
Hospital Mortality - trends
Humans
Incidence
Inpatients
Kidneys
Length of stay
Male
Mechanical ventilation
Medicine
Medicine & Public Health
Mental disorders
Mortality
Original Paper
Pacemakers
Patients
Postoperative Complications - epidemiology
Propensity Score
Prosthesis Design
Regression analysis
Regression models
Retrospective Studies
Risk
Sensitivity analysis
Statistical analysis
Transcatheter Aortic Valve Replacement - methods
Ventilation
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Summary:Introduction The effect of valve type on outcomes in transfemoral transcatheter aortic valve replacement (TF-TAVR) has recently been subject of debate. We investigate outcomes of patients treated with balloon-expanding (BE) vs. self-expanding (SE) valves in in a cohort of all these procedures performed in Germany in 2018. Methods All patients receiving TF-TAVR with either BE ( N  = 9,882) or SE ( N  = 7,413) valves in Germany in 2018 were identified. In-hospital outcomes were analyzed for the endpoints in-hospital mortality, major bleeding, stroke, acute kidney injury, postoperative delirium, permanent pacemaker implantation, mechanical ventilation > 48 h, length of hospital stay, and reimbursement. Since patients were not randomized to the two treatment options, logistic or linear regression models were used with 22 baseline patient characteristics and center-specific variables as potential confounders. As a sensitivity analysis, the same confounding factors were taken into account using the propensity score methods (inverse probability of treatment weighting). Results Baseline characteristics differed substantially, with higher EuroSCORE ( p  
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-021-01928-6