Autoimmune Progesterone Dermatitis

The condition autoimmune progesterone dermatitis (APD) is an immune disorder, observed among women, primarily due to progesterone surge during menstrual cycle. Here, we present a case of a 29-year-old female with recurrent severe skin eruptions associated with her menstrual cycle that commenced a fe...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2021-11, Vol.13 (11)
Main Authors: Irshad, Shahmeen, Haider, Muhammad S, Master, Madiha F, Asif, Nasir, Khalil, Ambreen
Format: Article
Language:English
Subjects:
Allergy/Immunology
Anaphylaxis
Autoimmune diseases
Birth control
Case reports
Dermatitis
Emergency medical care
Erythema
Internal Medicine
Medicine
Menstruation
Morphine
Pain
Patients
Skin
Steroids
Urticaria
Womens health
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Summary:The condition autoimmune progesterone dermatitis (APD) is an immune disorder, observed among women, primarily due to progesterone surge during menstrual cycle. Here, we present a case of a 29-year-old female with recurrent severe skin eruptions associated with her menstrual cycle that commenced a few years ago. She presented with blistered skin lesion of the body and also blisters in oropharyngeal mucosa leading to a variety of symptoms ranging from pruritus to difficulty in swallowing. Recognition of this process is important as it can result in significant debility among women. Our patient was treated with steroids and antihistamines to provide symptomatic relief and was encouraged to resume her oral contraceptive pill, which is a more definitive therapy.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.19217