Incidence of SARS‐CoV‐2 infection among asymptomatic patients undergoing preoperative COVID testing prior to cancer surgery: ASPECT study

• Published in: Journal of Surgical Oncology 2022-03, Vol.125 (4), p.564-569
• Main Authors: Patkar, Shraddha, Voppuru, Saiesh R., Thiagarajan, Shivakumar, Niyogi, Devayani, Niranjan, Hemant S., Nadkarni, Shravan, Singh, Tejpratap, Bhandare, Manish, Thakkar, Purvi, Rohila, Jitender, Biswas, Sanjay, Epari, Sridhar, Shetty, Omshree, Gurav, Mamta, Bapat, Prachi, Puri, Ajay, Pramesh, C. S.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Asymptomatic; Asymptomatic Infections - epidemiology; Cancer surgery; Child; Child, Preschool; Covid Corner; COVID-19; COVID-19 - complications; COVID-19 - diagnosis; COVID-19 - epidemiology; COVID-19 Testing; Female; Follow-Up Studies; Humans; Incidence; India - epidemiology; Infant; Infant, Newborn; Infections; Male; Middle Aged; Neoplasms - complications; Neoplasms - surgery; Postoperative Complications - diagnosis; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Postoperative period; Preoperative Care; Retrospective Studies; Risk Factors; SARS‐CoV‐2 infection; Severe acute respiratory syndrome coronavirus 2; Young Adult
• ISSN: 0022-4790; 1096-9098
• DOI: 10.1002/jso.26753

Background and Objectives The COVID‐19 pandemic, with high rate of asymptomatic infections and increased perioperative complications, prompted widespread adoption of screening methods. We analyzed the incidence of asymptomatic infection and perioperative outcomes in patients undergoing cancer surgery. We also studied the impact on subsequent cancer treatment in those with COVID‐19. Methods All patients who underwent elective and emergency cancer surgery from April to September 2020 were included. After screening for symptoms, a preoperative test was performed from nasopharyngeal and oropharyngeal swabs before the procedure. Patients were followed up for 30 days postoperatively and complications were noted. Results 2108 asymptomatic patients were tested, of which 200 (9.5%) tested positive. Of those who tested positive, 140 (70%) underwent the planned surgery at a median of 30 days from testing positive, and 20 (14.3%) had ≥ Grade III complications. Forty (20%) patients did not receive the intended treatment; 110 patients were retested in the Postoperative period, and 41 (37.3%) tested positive and 9(22%) patients died of COVID‐related complications. Conclusion Routine preoperative testing for COVID‐19 helps to segregate patients with asymptomatic infection. Higher complications occur in those who develop COVID‐19 in postoperative period. Prolonged delay in surgery after COVID infection may influence planned treatment.