The Effect of Buprenorphine on Human Immunodeficiency Virus Viral Suppression

Abstract Background Opioid use is prevalent among people living with human immunodeficiency virus (HIV; PLWH) and adversely affects HIV outcomes. We assessed the effect of buprenorphine (BUP) initiation on subsequent HIV viral loads. Methods We identified PLWH from the Johns Hopkins HIV Clinical Coh...

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Bibliographic Details
Published in:Clinical infectious diseases 2021-12, Vol.73 (11), p.1951-1956
Main Authors: Kim, Jongyeon, Lesko, Catherine R, Fojo, Anthony T, Keruly, Jeanne C, Moore, Richard D, Chander, Geetanjali, Lau, Bryan
Format: Article
Language:English
Subjects:
Anti-HIV Agents - therapeutic use
Buprenorphine - therapeutic use
HIV
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - epidemiology
Humans
Major and Commentaries
Opioid-Related Disorders - complications
Opioid-Related Disorders - drug therapy
Opioid-Related Disorders - epidemiology
Viral Load
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Summary:Abstract Background Opioid use is prevalent among people living with human immunodeficiency virus (HIV; PLWH) and adversely affects HIV outcomes. We assessed the effect of buprenorphine (BUP) initiation on subsequent HIV viral loads. Methods We identified PLWH from the Johns Hopkins HIV Clinical Cohort who initiated BUP between 2002 and 2017. Poisson regression with robust variance was used to estimate the prevalence of viral suppression (
ISSN:1058-4838
1537-6591
1537-6591
DOI:10.1093/cid/ciab578