Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in León, Nicaragua

In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselv...

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Bibliographic Details
Published in:Epidemiology & Infection 2021-10, Vol.149, p.e247-e247, Article e247
Main Authors: González, Fredman, Vielot, Nadja A., Sciaudone, Michael, Toval-Ruíz, Christian, Premkumar, Lakshmanane, Gutierrez, Lester, Cuadra, Edwing Centeno, Munguia, Nancy, Blandón, Patricia, de Silva, Aravinda M., Rubinstein, Rebecca, Bowman, Natalie, Becker-Dreps, Sylvia, Bucardo, Filemon
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age groups
Aged
Aged, 80 and over
Antibodies
Child
Child, Preschool
Cohort Studies
COVID-19 - epidemiology
Epidemics
Female
Households
Humans
Infections
Male
Middle Aged
Nicaragua - epidemiology
Pandemics
Population
Prevalence
Proteins
Public health
SARS-CoV-2 - isolation & purification
Seroepidemiologic Studies
Seroepidemiology
Serology
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Short Paper
Urban Population - statistics & numerical data
Urban populations
Young Adult
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Summary:In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268821002144