Determinants of left atrial reservoir and pump strain and use of atrial strain for evaluation of left ventricular filling pressure

• Published in: European heart journal cardiovascular imaging 2021-12, Vol.23 (1), p.61-70
• Main Authors: Inoue, Katsuji, Khan, Faraz H, Remme, Espen W, Ohte, Nobuyuki, García-Izquierdo, Eusebio, Chetrit, Michael, Moñivas-Palomero, Vanessa, Mingo-Santos, Susana, Andersen, Øyvind S, Gude, Einar, Andreassen, Arne K, Wang, Tom Kai Ming, Kikuchi, Shohei, Stugaard, Marie, Ha, Jong-Won, Klein, Allan L, Nagueh, Sherif F, Smiseth, Otto A
• Format: Article
• Language: English
• Subjects: Echocardiography; Heart Atria - diagnostic imaging; Humans; Original Papers; Stroke Volume; Systole; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Function, Left
• ISSN: 2047-2404; 2047-2412
• DOI: 10.1093/ehjci/jeaa415

Abstract Aims The aim of this study is to investigate determinants of left atrial (LA) reservoir and pump strain and if these parameters may serve as non-invasive markers of left ventricular (LV) filling pressure. Methods and results In a multicentre study of 322 patients with cardiovascular disease of different aetiologies, LA strain and other echocardiographic parameters were compared with invasively measured LV filling pressure. The strongest determinants of LA reservoir and pump strain were LV global longitudinal strain (GLS) (r-values 0.64 and 0.51, respectively) and LV filling pressure (r-values −0.52 and −0.57, respectively). Left atrial volume was another independent, but weaker determinant of both LA strains. For both LA strains, association with LV filling pressure was strongest in patients with reduced LV ejection fraction. Left atrial reservoir strain