Effects of aging on clinical outcomes in patients receiving genotype‐guided P2Y12 inhibitor selection after percutaneous coronary intervention

Study Objective To compare the clinical effectiveness of genotype‐guided P2Y12 inhibitor selection following PCI in older patients (≥70 years) and younger patients (

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Bibliographic Details
Published in:Pharmacotherapy 2021-12, Vol.41 (12), p.970-977
Main Authors: Wood, Brian, Lee, Craig R., Mulrenin, Ian R., Gower, Megan N., Rossi, Joseph S., Weck, Karen E., Stouffer, George A.
Format: Article
Language:English
Subjects:
Acute Coronary Syndrome - surgery
Acute coronary syndromes
Aged
Aging
Alleles
Angioplasty
Antiplatelet therapy
antiplatelets
Cardiovascular diseases
Clinical outcomes
Clopidogrel
coronary artery disease
Cytochrome P-450 CYP2C19 - genetics
Cytochrome P-450 CYP2C19 - therapeutic use
cytochrome P450
elderly
Genotype
Genotype & phenotype
Genotypes
Humans
Implants
Ischemia
Patients
Percutaneous Coronary Intervention
pharmacogenomics
Platelet Aggregation Inhibitors - therapeutic use
Population studies
Retrospective Studies
Thrombosis
Transient ischemic attack
Treatment Outcome
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Description
Summary:Study Objective To compare the clinical effectiveness of genotype‐guided P2Y12 inhibitor selection following PCI in older patients (≥70 years) and younger patients (
ISSN:0277-0008
1875-9114
DOI:10.1002/phar.2611