Invited Perspective: Phthalates and Blood Pressure: the Unknowns of Dietary Factors

(2021) indicate that phthalates may interfere with blood pressure regulation and that phthalates metabolites may act on different vasoactive pathways. [...]phthalates could have a distinct effect on blood pressure levels. [...]phthalate exposure may be relatively constant given these chemicals’ ubiq...

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Bibliographic Details
Published in:Environmental health perspectives 2021-12, Vol.129 (12), p.121303
Main Author: Arenas, Ivan A
Format: Article
Language:English
Subjects:
Blood Pressure
Body weight
Body weight gain
Consumer products
Diet
Exposure
Food
Food packaging
Food processing
Hypertension
Invited
Metabolites
Personal grooming
Pharmacists
Phthalate esters
Phthalates
Phthalic Acids - toxicity
Physiology
Potassium
Pregnancy
Pressure effects
Processed foods
Sodium
Vasoactive agents
Womens health
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Summary:(2021) indicate that phthalates may interfere with blood pressure regulation and that phthalates metabolites may act on different vasoactive pathways. [...]phthalates could have a distinct effect on blood pressure levels. [...]phthalate exposure may be relatively constant given these chemicals’ ubiquitous presence in food packaging and personal care products (Wittassek et al. 2007). [...]the impact of any interaction or confounding of phthalates with major dietary determinants of blood pressure (e.g., sodium, potassium, calcium, caloric intake) is unclear and was not evaluated in the study by Wu et al. (2014), the association of phthalate metabolites and obesity parameters may be confounded by covariation of body weight and dietary composition (e.g., processed vs. unprocessed foods) and phthalate exposure. [...]women with higher blood pressure during or after pregnancy may have experienced higher weight gain, higher caloric and sodium intake, and higher phthalate exposure (e.g., from processed foods).
ISSN:0091-6765
1552-9924
DOI:10.1289/EHP10172