Cost-Effectiveness of Nutrient Supplementation in Cancer Survivors

Cancer patients are at risk for malnutrition; the aim of this study was to provide a cost-effectiveness analysis of dietary supplementation in cancer survivors. We estimated prevalence of supplementation, hospitalization rates, quality of life (QOL), cost of care and mortality among cancer survivors...

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Bibliographic Details
Published in:Cancers 2021-12, Vol.13 (24), p.6276
Main Authors: Shaver, Amy L, Tufuor, Theresa A, Nie, Jing, Ekimura, Shauna, Marshall, Keri, Mitmesser, Susan Hazels, Noyes, Katia
Format: Article
Language:English
Subjects:
Age
Body mass index
Cancer
Cancer therapies
Chronic obstructive pulmonary disease
Cost analysis
Dietary supplements
Education
Estimates
Health care
Health care expenditures
Health care policy
Health insurance
Hospitalization
Insurance coverage
Interviews
Life expectancy
Malnutrition
Medicaid
Medicare
Nutrients
Nutrition
Patients
Population
Quality of life
Sensitivity analysis
Vitamins
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Summary:Cancer patients are at risk for malnutrition; the aim of this study was to provide a cost-effectiveness analysis of dietary supplementation in cancer survivors. We estimated prevalence of supplementation, hospitalization rates, quality of life (QOL), cost of care and mortality among cancer survivors. We built a decision analytic model to simulate life-long costs of health care and supplementation and QOL among cancer survivors with and without supplementation. Cost of supplements was derived from national pharmacy databases including single- and multivitamin formularies. One-way and probabilistic sensitivity analysis were performed to evaluate the robustness of the incremental cost-effectiveness ratio (ICER) to changes in supplementation costs and duration. The study cohort represented the national cancer survivor population (average age 61 years, 85% white, 52% male, and 94% insured). Hospitalization rates for supplement users and non-users were 12% and 21%, respectively. The cost of hospitalization was $4030. Supplementation was associated with an additional 0.48 QALYs (10.26 vs. 9.78) at the incremental cost of $2094 ($236,933 vs. $234,839) over the remaining lifetime of survivors (on average 13 years). Adequate nutrition provides a cost-effective strategy to achieving potentially optimum health. Further studies are needed to determine the effects of specific nutrient doses and supplementation on long-term outcomes per cancer type.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers13246276