Newly Developed Psoriasis in a Patient with Telangiectasia Macularis Eruptiva Perstans and Systemic Mastocytosis Treated with Interferon

The authors present a rare case of a patient with telangiectasia macular eruptiva perstans, with confirmed D816V mutation which later progressed to systemic mastocytosis confirmed by trepanobiopsy. First-line treatment – phototherapy – had to be stopped, and systemic treatment with interferon alpha-...

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Published in:Case reports in dermatology 2021-12, Vol.13 (3), p.558-562
Main Authors: Péčová, Tatiana, Burjanivová, Tatiana, Malicherová, Bibiana, Péč, Martin Jozef, Rohoň, Igor, Madleňák, Matúš, Adamicová, Katarína, Péč, Juraj
Format: Article
Language:English
Subjects:
Biopsy
Blood vessels
Bone marrow
Case reports
Cell growth
Disease
Interferon
Lymphocytes
mastocytosis
Mutation
Psoriasis
Single Case
Skin
telangiectasia macularis eruptiva perstans
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container_title Case reports in dermatology
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creator Péčová, Tatiana
Burjanivová, Tatiana
Malicherová, Bibiana
Péč, Martin Jozef
Rohoň, Igor
Madleňák, Matúš
Adamicová, Katarína
Péč, Juraj
description The authors present a rare case of a patient with telangiectasia macular eruptiva perstans, with confirmed D816V mutation which later progressed to systemic mastocytosis confirmed by trepanobiopsy. First-line treatment – phototherapy – had to be stopped, and systemic treatment with interferon alpha-2a was initiated. The treatment was successful with regression of skin lesions as well as mast cell infiltrates in the bone marrow. However, the treatment was complicated by the onset of psoriasis lesions.
doi_str_mv 10.1159/000520533
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subjects Biopsy
Blood vessels
Bone marrow
Case reports
Cell growth
Disease
Interferon
Lymphocytes
mastocytosis
Mutation
Psoriasis
Single Case
Skin
telangiectasia macularis eruptiva perstans
title Newly Developed Psoriasis in a Patient with Telangiectasia Macularis Eruptiva Perstans and Systemic Mastocytosis Treated with Interferon
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