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Evaluation of pediatric hydrocephalus: Clinical, surgical, and outcome perspective in a tertiary center
Context: Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population. Aims: The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age
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| Published in: | Asian journal of neurosurgery 2021-10, Vol.16 (4), p.706-713 |
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| Main Authors: | , , , , , |
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| container_end_page | 713 |
| container_issue | 4 |
| container_start_page | 706 |
| container_title | Asian journal of neurosurgery |
| container_volume | 16 |
| creator | Singh, Rahul Prasad, Ravi Singh, Ramit Trivedi, Adarsh Bhaikhel, Kulwant Sahu, Anurag |
| description | Context:
Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population.
Aims:
The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age |
| doi_str_mv | 10.4103/ajns.AJNS_132_21 |
| format | article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8751515</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A687568842</galeid><sourcerecordid>A687568842</sourcerecordid><originalsourceid>FETCH-LOGICAL-c438i-f522284ba647dca9d46af6b67588ddf5d7e45a37f7c2387d4d6dc414a6214c73</originalsourceid><addsrcrecordid>eNp1ks1v2yAYxtG0aY263neaLE2adphTgzE4O0zKou5L1XZY74jA65gUQwp2ov73w3JbJdJqDkbwex7gfR-E3uJiTnFRXsqti_Plr99_BS6JIPgFmhFC63zBMH2JZpgvyryiNTlDFzFui_RVuKoK8hqdlVXBccHYDG2u9tIOsjfeZb7JdqCN7INRWXuvg1ewa9N2_JytrHFGSfspi0PYTDPpdOaHXvkOkjDEHaje7CEzLpNZD6E3MtxnClyav0GvGmkjXDz8z9HNt6ub1Y_8-s_3n6vlda5oWZu8qQghNV1LRrlWcqEpkw1bM17VtdZNpTnQSpa84YqUNddUM60oppIRTBUvz9GXyXY3rDvQ49lBWrELpkt3EV4acbrjTCs2fi9qnoqDq2Tw8cEg-LsBYi86ExVYKx34IQrCUo15ScrxrPcTupEWhHGNT45qxMWSJT9W15Qkav4fKg0NnVHeQWPS-ongw5GgBWn7Nno7jC2Kp2AxgSr4GAM0T8_EhRgTIsaEiKOEJMm74_I8CR7zkICvE3DwNnUt3trhAEEk9tb5w7PGghdMPCYpmVxOJn1roAOx9UNwqenP3-sfuMjfMg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2622473237</pqid></control><display><type>article</type><title>Evaluation of pediatric hydrocephalus: Clinical, surgical, and outcome perspective in a tertiary center</title><source>PubMed Central Free</source><creator>Singh, Rahul ; Prasad, Ravi ; Singh, Ramit ; Trivedi, Adarsh ; Bhaikhel, Kulwant ; Sahu, Anurag</creator><creatorcontrib>Singh, Rahul ; Prasad, Ravi ; Singh, Ramit ; Trivedi, Adarsh ; Bhaikhel, Kulwant ; Sahu, Anurag</creatorcontrib><description>Context:
Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population.
Aims:
The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age <12 years.
Settings and Design:
This is a retrospective cohort study. Materials and
Methods:
This study includes 117 pediatric patients (age ≤12 years) of hydrocephalus due to various etiology admitted in our department between September 2018 and December 2020. Demographic profile, etiology, clinical presentation, management, complications and postoperative outcome characteristics were evaluated. Survival analysis was done with respect to etiology and age group. Statistical Analysis Used: P < 0.05 was considered statistically significant. Unpaired t-test and Chi-square test were used. Kaplan–Meier curve plotting and survival analysis were also done.
Results:
Male-to-female ratio was 1.3:1. Most frequent etiology of PH was postinfectious (35%). Posterior fossa pilocytic astrocytoma (34.2%) was the most common neoplastic etiology. Surgical procedure performed for PH was ventriculoperitoneal shunting (n = 103), Ommaya reservoir (n = 2) placement, and endoscopic third ventriculostomy (ETV) (n = 8). Mortality was significantly (P = 0.0139) more in patients of neoplastic etiology. Cognitive deficits and delayed developmental milestones were significantly (P < 0.05) more in congenital hydrocephalus etiology. There was a nonsignificant difference in survival between age groups (P = 0.1971). However, a significant survival difference was evident (P = 0.0098) for etiology.
Conclusions:
Disease-specific mortality is main cause of mortality in PH. Neoplastic etiology PH has poor survival when compared to others. Life-long routine controls are required to avoid future possible complications and enhance better rehabilitation of the child.</description><identifier>ISSN: 1793-5482</identifier><identifier>EISSN: 2248-9614</identifier><identifier>DOI: 10.4103/ajns.AJNS_132_21</identifier><identifier>PMID: 35071066</identifier><language>eng</language><publisher>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India: Thieme Medical and Scientific Publishers Pvt. Ltd</publisher><subject>Children ; Health aspects ; Hydrocephalus ; Medical research ; Medicine, Experimental ; Original ; Original Article ; Patient outcomes ; Pediatrics</subject><ispartof>Asian journal of neurosurgery, 2021-10, Vol.16 (4), p.706-713</ispartof><rights>Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon.</rights><rights>Copyright: © 2021 Asian Journal of Neurosurgery.</rights><rights>COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright: © 2021 Asian Journal of Neurosurgery 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438i-f522284ba647dca9d46af6b67588ddf5d7e45a37f7c2387d4d6dc414a6214c73</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751515/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751515/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35071066$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Singh, Rahul</creatorcontrib><creatorcontrib>Prasad, Ravi</creatorcontrib><creatorcontrib>Singh, Ramit</creatorcontrib><creatorcontrib>Trivedi, Adarsh</creatorcontrib><creatorcontrib>Bhaikhel, Kulwant</creatorcontrib><creatorcontrib>Sahu, Anurag</creatorcontrib><title>Evaluation of pediatric hydrocephalus: Clinical, surgical, and outcome perspective in a tertiary center</title><title>Asian journal of neurosurgery</title><addtitle>Asian J Neurosurg</addtitle><description>Context:
Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population.
Aims:
The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age <12 years.
Settings and Design:
This is a retrospective cohort study. Materials and
Methods:
This study includes 117 pediatric patients (age ≤12 years) of hydrocephalus due to various etiology admitted in our department between September 2018 and December 2020. Demographic profile, etiology, clinical presentation, management, complications and postoperative outcome characteristics were evaluated. Survival analysis was done with respect to etiology and age group. Statistical Analysis Used: P < 0.05 was considered statistically significant. Unpaired t-test and Chi-square test were used. Kaplan–Meier curve plotting and survival analysis were also done.
Results:
Male-to-female ratio was 1.3:1. Most frequent etiology of PH was postinfectious (35%). Posterior fossa pilocytic astrocytoma (34.2%) was the most common neoplastic etiology. Surgical procedure performed for PH was ventriculoperitoneal shunting (n = 103), Ommaya reservoir (n = 2) placement, and endoscopic third ventriculostomy (ETV) (n = 8). Mortality was significantly (P = 0.0139) more in patients of neoplastic etiology. Cognitive deficits and delayed developmental milestones were significantly (P < 0.05) more in congenital hydrocephalus etiology. There was a nonsignificant difference in survival between age groups (P = 0.1971). However, a significant survival difference was evident (P = 0.0098) for etiology.
Conclusions:
Disease-specific mortality is main cause of mortality in PH. Neoplastic etiology PH has poor survival when compared to others. Life-long routine controls are required to avoid future possible complications and enhance better rehabilitation of the child.</description><subject>Children</subject><subject>Health aspects</subject><subject>Hydrocephalus</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Original</subject><subject>Original Article</subject><subject>Patient outcomes</subject><subject>Pediatrics</subject><issn>1793-5482</issn><issn>2248-9614</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>0U6</sourceid><recordid>eNp1ks1v2yAYxtG0aY263neaLE2adphTgzE4O0zKou5L1XZY74jA65gUQwp2ov73w3JbJdJqDkbwex7gfR-E3uJiTnFRXsqti_Plr99_BS6JIPgFmhFC63zBMH2JZpgvyryiNTlDFzFui_RVuKoK8hqdlVXBccHYDG2u9tIOsjfeZb7JdqCN7INRWXuvg1ewa9N2_JytrHFGSfspi0PYTDPpdOaHXvkOkjDEHaje7CEzLpNZD6E3MtxnClyav0GvGmkjXDz8z9HNt6ub1Y_8-s_3n6vlda5oWZu8qQghNV1LRrlWcqEpkw1bM17VtdZNpTnQSpa84YqUNddUM60oppIRTBUvz9GXyXY3rDvQ49lBWrELpkt3EV4acbrjTCs2fi9qnoqDq2Tw8cEg-LsBYi86ExVYKx34IQrCUo15ScrxrPcTupEWhHGNT45qxMWSJT9W15Qkav4fKg0NnVHeQWPS-ongw5GgBWn7Nno7jC2Kp2AxgSr4GAM0T8_EhRgTIsaEiKOEJMm74_I8CR7zkICvE3DwNnUt3trhAEEk9tb5w7PGghdMPCYpmVxOJn1roAOx9UNwqenP3-sfuMjfMg</recordid><startdate>20211001</startdate><enddate>20211001</enddate><creator>Singh, Rahul</creator><creator>Prasad, Ravi</creator><creator>Singh, Ramit</creator><creator>Trivedi, Adarsh</creator><creator>Bhaikhel, Kulwant</creator><creator>Sahu, Anurag</creator><general>Thieme Medical and Scientific Publishers Pvt. Ltd</general><general>Wolters Kluwer India Pvt. Ltd</general><general>Medknow Publications and Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><scope>0U6</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20211001</creationdate><title>Evaluation of pediatric hydrocephalus: Clinical, surgical, and outcome perspective in a tertiary center</title><author>Singh, Rahul ; Prasad, Ravi ; Singh, Ramit ; Trivedi, Adarsh ; Bhaikhel, Kulwant ; Sahu, Anurag</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438i-f522284ba647dca9d46af6b67588ddf5d7e45a37f7c2387d4d6dc414a6214c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Children</topic><topic>Health aspects</topic><topic>Hydrocephalus</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Original</topic><topic>Original Article</topic><topic>Patient outcomes</topic><topic>Pediatrics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Singh, Rahul</creatorcontrib><creatorcontrib>Prasad, Ravi</creatorcontrib><creatorcontrib>Singh, Ramit</creatorcontrib><creatorcontrib>Trivedi, Adarsh</creatorcontrib><creatorcontrib>Bhaikhel, Kulwant</creatorcontrib><creatorcontrib>Sahu, Anurag</creatorcontrib><collection>Thieme Connect Journals Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Asian journal of neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Singh, Rahul</au><au>Prasad, Ravi</au><au>Singh, Ramit</au><au>Trivedi, Adarsh</au><au>Bhaikhel, Kulwant</au><au>Sahu, Anurag</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of pediatric hydrocephalus: Clinical, surgical, and outcome perspective in a tertiary center</atitle><jtitle>Asian journal of neurosurgery</jtitle><addtitle>Asian J Neurosurg</addtitle><date>2021-10-01</date><risdate>2021</risdate><volume>16</volume><issue>4</issue><spage>706</spage><epage>713</epage><pages>706-713</pages><issn>1793-5482</issn><eissn>2248-9614</eissn><abstract>Context:
Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population.
Aims:
The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age <12 years.
Settings and Design:
This is a retrospective cohort study. Materials and
Methods:
This study includes 117 pediatric patients (age ≤12 years) of hydrocephalus due to various etiology admitted in our department between September 2018 and December 2020. Demographic profile, etiology, clinical presentation, management, complications and postoperative outcome characteristics were evaluated. Survival analysis was done with respect to etiology and age group. Statistical Analysis Used: P < 0.05 was considered statistically significant. Unpaired t-test and Chi-square test were used. Kaplan–Meier curve plotting and survival analysis were also done.
Results:
Male-to-female ratio was 1.3:1. Most frequent etiology of PH was postinfectious (35%). Posterior fossa pilocytic astrocytoma (34.2%) was the most common neoplastic etiology. Surgical procedure performed for PH was ventriculoperitoneal shunting (n = 103), Ommaya reservoir (n = 2) placement, and endoscopic third ventriculostomy (ETV) (n = 8). Mortality was significantly (P = 0.0139) more in patients of neoplastic etiology. Cognitive deficits and delayed developmental milestones were significantly (P < 0.05) more in congenital hydrocephalus etiology. There was a nonsignificant difference in survival between age groups (P = 0.1971). However, a significant survival difference was evident (P = 0.0098) for etiology.
Conclusions:
Disease-specific mortality is main cause of mortality in PH. Neoplastic etiology PH has poor survival when compared to others. Life-long routine controls are required to avoid future possible complications and enhance better rehabilitation of the child.</abstract><cop>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India</cop><pub>Thieme Medical and Scientific Publishers Pvt. Ltd</pub><pmid>35071066</pmid><doi>10.4103/ajns.AJNS_132_21</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Children Health aspects Hydrocephalus Medical research Medicine, Experimental Original Original Article Patient outcomes Pediatrics |
| title | Evaluation of pediatric hydrocephalus: Clinical, surgical, and outcome perspective in a tertiary center |
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