Combination of cycle threshold time, absolute lymphocyte count and neutrophil:lymphocyte ratio is predictive of hypoxia in patients with SARS-CoV-2 infection

Abstract Background There is currently no clinically validated biomarker to predict respiratory compromise in sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Cycle threshold time (Ct), absolute lymphocyte count (AL) and neutrophil:lymphocyte ratio (NLR) have been previously e...

Full description

Saved in:
Bibliographic Details
Published in:Transactions of the Royal Society of Tropical Medicine and Hygiene 2022-07, Vol.116 (7), p.628-635
Main Authors: Abeysuriya, Visula, Seneviratne, Suranjith L, de Silva, Arjuna P, Mowjood, Riaz, Mowjood, Shazli, de Silva, Thushara, de Mel, Primesh, de Mel, Chandima, Chandrasena, Lal, Wijesinha, R S, Fernando, Amitha, de Mel, Sanjay
Format: Article
Language:English
Subjects:
COVID-19 - diagnosis
Humans
Hypoxia
Lymphocyte Count
Lymphocytes
Neutrophils
Original
Prognosis
Retrospective Studies
ROC Curve
SARS-CoV-2
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Background There is currently no clinically validated biomarker to predict respiratory compromise in sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Cycle threshold time (Ct), absolute lymphocyte count (AL) and neutrophil:lymphocyte ratio (NLR) have been previously evaluated for this purpose. We hypothesized that the combination of these parameters at presentation may be predictive of hypoxia (oxygen saturation
ISSN:0035-9203
1878-3503
DOI:10.1093/trstmh/trab182