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Wounds in chronic leg oedema
Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross‐sectional study was to investigate the point‐prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic le...
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Published in: | International wound journal 2022-02, Vol.19 (2), p.411-425 |
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description | Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross‐sectional study was to investigate the point‐prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63‐6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25‐3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93‐3.60), being male (OR 2.08, 95% CI 1.78‐2.44), being over 85 years of age (OR 1.80, 95% CI 1.23‐2.62), underweight (OR 1.79, 95% CI 1.14‐2.79), bed bound (OR 1.79, 95% CI 1.01‐3.16), chair bound (OR 1.52, 95% CI 1.18‐1.97), diabetes (OR 1.47, 95% CI 1.23‐1.77), and walking with aid (OR 1·41, 95% CI 1.17‐1.69). 43.22% of those with wounds had clinically defined well‐controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42‐0.58, P |
doi_str_mv | 10.1111/iwj.13642 |
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The objective of this cross‐sectional study was to investigate the point‐prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63‐6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25‐3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93‐3.60), being male (OR 2.08, 95% CI 1.78‐2.44), being over 85 years of age (OR 1.80, 95% CI 1.23‐2.62), underweight (OR 1.79, 95% CI 1.14‐2.79), bed bound (OR 1.79, 95% CI 1.01‐3.16), chair bound (OR 1.52, 95% CI 1.18‐1.97), diabetes (OR 1.47, 95% CI 1.23‐1.77), and walking with aid (OR 1·41, 95% CI 1.17‐1.69). 43.22% of those with wounds had clinically defined well‐controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42‐0.58, P < .001). Hard/fibrotic tissue (OR 1.71, 95% CI 1.19‐2.48), and a positive Stemmers sign (OR 1.57, 95% CI 1.05‐2.35) were associated with wounds. The study reinforces the importance of measures to control oedema, as controlled swelling was associated with a 50% lower risk of wounds.</description><identifier>ISSN: 1742-4801</identifier><identifier>EISSN: 1742-481X</identifier><identifier>DOI: 10.1111/iwj.13642</identifier><identifier>PMID: 34258856</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Body mass index ; Cancer ; Cellulitis ; Chronic Disease ; chronic oedema ; Compression therapy ; Cross-Sectional Studies ; Dermatology ; Edema ; Edema - epidemiology ; Edema - etiology ; Hippocrates (460?-377? BC) ; Human health and pathology ; Humans ; Leg ; Leg ulcers ; Legs ; Life Sciences ; LIMPRINT ; Lymphedema ; Lymphedema - epidemiology ; lymphoedema ; Male ; Medical records ; Obesity ; Original ; Patients ; Risk factors ; Surgery ; Variables ; Wound healing ; wounds and injuries</subject><ispartof>International wound journal, 2022-02, Vol.19 (2), p.411-425</ispartof><rights>2021 The Authors. published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.</rights><rights>2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.</rights><rights>2022. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Attribution - NonCommercial - NoDerivatives</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4772-3cb65b6c65c45c8abc3719cd5d4b18d21c01948ab782df7b3e75da5ad7564aa03</citedby><cites>FETCH-LOGICAL-c4772-3cb65b6c65c45c8abc3719cd5d4b18d21c01948ab782df7b3e75da5ad7564aa03</cites><orcidid>0000-0002-9782-0181 ; 0000-0003-0630-2694 ; 0000-0002-1492-9764</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762561/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762561/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,11541,27901,27902,46027,46451,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34258856$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-04557410$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Burian, Ewa Anna</creatorcontrib><creatorcontrib>Karlsmark, Tonny</creatorcontrib><creatorcontrib>Nørregaard, Susan</creatorcontrib><creatorcontrib>Kirketerp‐Møller, Klaus</creatorcontrib><creatorcontrib>Kirsner, Robert Scott</creatorcontrib><creatorcontrib>Franks, Peter John</creatorcontrib><creatorcontrib>Quéré, Isabelle</creatorcontrib><creatorcontrib>Moffatt, Christine Joy</creatorcontrib><title>Wounds in chronic leg oedema</title><title>International wound journal</title><addtitle>Int Wound J</addtitle><description>Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross‐sectional study was to investigate the point‐prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63‐6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25‐3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93‐3.60), being male (OR 2.08, 95% CI 1.78‐2.44), being over 85 years of age (OR 1.80, 95% CI 1.23‐2.62), underweight (OR 1.79, 95% CI 1.14‐2.79), bed bound (OR 1.79, 95% CI 1.01‐3.16), chair bound (OR 1.52, 95% CI 1.18‐1.97), diabetes (OR 1.47, 95% CI 1.23‐1.77), and walking with aid (OR 1·41, 95% CI 1.17‐1.69). 43.22% of those with wounds had clinically defined well‐controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42‐0.58, P < .001). Hard/fibrotic tissue (OR 1.71, 95% CI 1.19‐2.48), and a positive Stemmers sign (OR 1.57, 95% CI 1.05‐2.35) were associated with wounds. The study reinforces the importance of measures to control oedema, as controlled swelling was associated with a 50% lower risk of wounds.</description><subject>Body mass index</subject><subject>Cancer</subject><subject>Cellulitis</subject><subject>Chronic Disease</subject><subject>chronic oedema</subject><subject>Compression therapy</subject><subject>Cross-Sectional Studies</subject><subject>Dermatology</subject><subject>Edema</subject><subject>Edema - epidemiology</subject><subject>Edema - etiology</subject><subject>Hippocrates (460?-377? 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BC)</topic><topic>Human health and pathology</topic><topic>Humans</topic><topic>Leg</topic><topic>Leg ulcers</topic><topic>Legs</topic><topic>Life Sciences</topic><topic>LIMPRINT</topic><topic>Lymphedema</topic><topic>Lymphedema - epidemiology</topic><topic>lymphoedema</topic><topic>Male</topic><topic>Medical records</topic><topic>Obesity</topic><topic>Original</topic><topic>Patients</topic><topic>Risk factors</topic><topic>Surgery</topic><topic>Variables</topic><topic>Wound healing</topic><topic>wounds and injuries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burian, Ewa Anna</creatorcontrib><creatorcontrib>Karlsmark, Tonny</creatorcontrib><creatorcontrib>Nørregaard, Susan</creatorcontrib><creatorcontrib>Kirketerp‐Møller, Klaus</creatorcontrib><creatorcontrib>Kirsner, Robert Scott</creatorcontrib><creatorcontrib>Franks, Peter John</creatorcontrib><creatorcontrib>Quéré, Isabelle</creatorcontrib><creatorcontrib>Moffatt, Christine Joy</creatorcontrib><collection>Open Access: Wiley-Blackwell Open Access Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International wound journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burian, Ewa Anna</au><au>Karlsmark, Tonny</au><au>Nørregaard, Susan</au><au>Kirketerp‐Møller, Klaus</au><au>Kirsner, Robert Scott</au><au>Franks, Peter John</au><au>Quéré, Isabelle</au><au>Moffatt, Christine Joy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wounds in chronic leg oedema</atitle><jtitle>International wound journal</jtitle><addtitle>Int Wound J</addtitle><date>2022-02</date><risdate>2022</risdate><volume>19</volume><issue>2</issue><spage>411</spage><epage>425</epage><pages>411-425</pages><issn>1742-4801</issn><eissn>1742-481X</eissn><abstract>Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross‐sectional study was to investigate the point‐prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63‐6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25‐3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93‐3.60), being male (OR 2.08, 95% CI 1.78‐2.44), being over 85 years of age (OR 1.80, 95% CI 1.23‐2.62), underweight (OR 1.79, 95% CI 1.14‐2.79), bed bound (OR 1.79, 95% CI 1.01‐3.16), chair bound (OR 1.52, 95% CI 1.18‐1.97), diabetes (OR 1.47, 95% CI 1.23‐1.77), and walking with aid (OR 1·41, 95% CI 1.17‐1.69). 43.22% of those with wounds had clinically defined well‐controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42‐0.58, P < .001). Hard/fibrotic tissue (OR 1.71, 95% CI 1.19‐2.48), and a positive Stemmers sign (OR 1.57, 95% CI 1.05‐2.35) were associated with wounds. The study reinforces the importance of measures to control oedema, as controlled swelling was associated with a 50% lower risk of wounds.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>34258856</pmid><doi>10.1111/iwj.13642</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-9782-0181</orcidid><orcidid>https://orcid.org/0000-0003-0630-2694</orcidid><orcidid>https://orcid.org/0000-0002-1492-9764</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Body mass index Cancer Cellulitis Chronic Disease chronic oedema Compression therapy Cross-Sectional Studies Dermatology Edema Edema - epidemiology Edema - etiology Hippocrates (460?-377? BC) Human health and pathology Humans Leg Leg ulcers Legs Life Sciences LIMPRINT Lymphedema Lymphedema - epidemiology lymphoedema Male Medical records Obesity Original Patients Risk factors Surgery Variables Wound healing wounds and injuries |
title | Wounds in chronic leg oedema |
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