Improved Performance of Compartments in Detecting the Activity of Axial Spondyloarthritis Based on IVIM DWI with Optimized Threshold b Value

Purpose. To explore the diagnostic performance of the optimized threshold b values on IVIM to detect the activity in axial spondyloarthritis (axSpA) patients. Method. 40 axSpA patients in the active group, 144 axSpA patients in the inactive group, and 20 healthy volunteers were used to evaluate the...

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Bibliographic Details
Published in:BioMed research international 2022, Vol.2022 (1), p.2276102-2276102
Main Authors: Ye, Qiang, Xie, Zhuoyao, Guo, Chang, Lu, Xing, Zheng, Kai, Zhao, Yinghua
Format: Article
Language:English
Subjects:
Active control
Adult
Arthritis
Axial Spondyloarthritis - diagnostic imaging
Biomedical research
Development and progression
Diagnosis
Diagnosis, Differential
Diagnostic systems
Diffusion coefficient
Diffusion Magnetic Resonance Imaging
Female
Humans
Inflammatory diseases
Kruskal-Wallis test
Magnetic resonance imaging
Male
Methods
Middle Aged
Performance evaluation
Perfusion
Prospective Studies
Rheumatic diseases
Sacroiliitis
Signal to noise ratio
Spondyloarthropathies
Statistical analysis
Variance analysis
Work stations
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Summary:Purpose. To explore the diagnostic performance of the optimized threshold b values on IVIM to detect the activity in axial spondyloarthritis (axSpA) patients. Method. 40 axSpA patients in the active group, 144 axSpA patients in the inactive group, and 20 healthy volunteers were used to evaluate the tissue diffusion coefficient (Dslow), perfusion fraction (f), and pseudodiffusion coefficient (Dfast) with b thresholds of 10, 20, and 30 s/mm2. The Kruskal-Wallis test and one way ANOVA test was used to compare the different activity among the three groups in axSpA patients, and receiver operating characteristic (ROC) curve analysis was applied to evaluate the performance for Dslow, f, and Dfast to detect the activity in axSpA patients, respectively. Results. Dslow demonstrated a statistical difference between two groups (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2022/2276102