Association between dyspeptic symptoms and endoscopic findings based on the Kyoto classification of gastritis in Japanese male

The Kyoto gastritis classification is used to categorize the endoscopic characteristics of Helicobacter pylori infection-associated gastritis. We aimed to clarify the association among endoscopic findings and abdominal dyspeptic symptoms in Japanese male. We administered a questionnaire to 418 subje...

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Bibliographic Details
Published in:Journal of Clinical Biochemistry and Nutrition 2022, Vol.70(1), pp.79-85
Main Authors: Takahashi, Kouji, Sugimoto, Mitsushige, Kawai, Yusuke, Hamada, Mariko, Iwata, Eri, Niikura, Ryota, Nagata, Naoyoshi, Fukuzawa, Masakatsu, Itoi, Takao, Ohtsubo, Tetsuo, Kawai, Takashi
Format: Article
Language:English
Subjects:
abdominal symptom
Classification
Confidence intervals
Endoscopy
Esophagus
Gastritis
Glands
Helicobacter pylori
Kyoto classification
Males
Original
Polyps
Questionnaires
Regression analysis
Risk analysis
Risk factors
Statistical analysis
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Summary:The Kyoto gastritis classification is used to categorize the endoscopic characteristics of Helicobacter pylori infection-associated gastritis. We aimed to clarify the association among endoscopic findings and abdominal dyspeptic symptoms in Japanese male. We administered a questionnaire to 418 subjects who underwent endoscopy as part of a health check-up from August 2003 to April 2004 to investigate the association among endoscopic findings of the Kyoto classification and the presence of dyspeptic symptoms. Logistic regression analyses were performed to evaluate risk based on dyspeptic symptoms. Among 418 health check-up subjects, 21.3% (89/418) reported dyspeptic symptoms in the questionnaire. The incidence of fundic gland polyp among patients with dyspeptic symptoms was 12.4% (11/89), which was significantly higher than that among non-symptomatic subjects (4.3%, 14/329, p = 0.004). Logistic regression analyses showed that fundic gland polyp was a risk factor for dyspeptic symptoms [odds ratio (OR): 3.413, 95% confidence interval (CI): 1.430–8.142], while short-segment Barrett’s esophagus and male sex were protective factors (OR: 0.569, 95% CI: 0.349–0.928 and OR: 0.333, 95% CI: 0.117–0.948, respectively). In conclusion, Endoscopic findings of fundic gland polyp may be associated with dyspeptic symptoms, which in turn may be a useful marker of gastric condition.
ISSN:0912-0009
1880-5086
DOI:10.3164/jcbn.21-79