Sleep disordered breathing from preschool to early adult age and its neurocognitive complications: A preliminary report

• Published in: Sleep science (São Paulo, SP ) SP ), 2021-01, Vol.14 (S 02), p.140-149
• Main Authors: Astara, Kyriaki, Siachpazidou, Dimitra, Vavougios, George D, Ragias, Dimitrios, Vatzia, Konstantina, Rapti, Georgia, Alexopoulos, Emmanouil, Gourgoulianis, Konstantinos I, Xiromerisiou, Georgia
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 1984-0659; 1984-0063
• DOI: 10.5935/1984-0063.20200098

Objective The onset and development of sleep disordered breathing (SDB) remains unclear in an age - dependent manner. Despite treatment, persistent symptoms such as snoring and excessive daytime sleepiness, as well as cognitive impairment may be present. The aim of the research was to determine the prevalence of residual symptoms of SDB in adolescence and early adulthood, the predisposing factors and its neurocognitive complications. Methods In the present pilot study-cohort, a questionnaire was utilized to 154 people (average age: 17.9 ± 3), who as children (mean age: 5.3 ± 1.4) had AHI ≥2.5 episodes/h. They were divided into two groups based on AHI = 5 episodes/h. Depending on the results, they were invited to undergo a repeated polysomnography (PSG) and complete the Montreal Cognitive Assessment (MoCA) test. Statistical analysis was made with IBM SPSS software. Results Out of the total, 35.7% claimed to still snore. AHI was negatively correlated to the severity of residual symptoms (Mann-Witney U test, p