Quality of life and mortality among survivors of acute respiratory distress syndrome in South Korea: a nationwide cohort study

Purpose Worsening quality of life (QOL) is an important health issue in acute respiratory distress syndrome (ARDS) survivors. We aimed to investigate the prevalence of worsening QOL among ARDS survivors and their association with mortality. Methods South Korean National Health Insurance database inf...

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Bibliographic Details
Published in:Journal of anesthesia 2022-04, Vol.36 (2), p.230-238
Main Authors: Choi, Hey-ran, Song, In-Ae, Oh, Tak Kyu
Format: Article
Language:English
Subjects:
Acute respiratory distress syndrome
Adult
Anesthesiology
Cohort Studies
Critical Care Medicine
Emergency Medicine
Humans
Intensive
Medicine
Medicine & Public Health
National health insurance
Original
Original Article
Pain Medicine
Quality of Life
Republic of Korea - epidemiology
Respiratory Distress Syndrome
South Korea
Survivors
Unemployment
United Kingdom
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Summary:Purpose Worsening quality of life (QOL) is an important health issue in acute respiratory distress syndrome (ARDS) survivors. We aimed to investigate the prevalence of worsening QOL among ARDS survivors and their association with mortality. Methods South Korean National Health Insurance database information for all adults admitted to intensive care units for ARDS from January 1, 2010 to December 31, 2018 who survived ≥ 365 days were included in this study. Results A total of 4452 ARDS survivors were included in the final analysis. Total QOL had worsened in 1667 (37.4%) of the survivors at the follow-up 1 year after being diagnosed with the syndrome. Specifically, 1298 patients (29.2%) experienced decreased income, 334 (7.5%) lost their jobs, and 327 (7.3%) had newly acquired disabilities. In the multivariable Cox regression analysis, worsening QOL was not associated with 2-year all-cause mortality among survivors ( P  = 0.140). However, newly acquired disability was associated with 1.74-fold (hazard ratio [HR]: 1.74, 95% confidence interval [CI] 1.31–2.33; P  
ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-022-03036-9