Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge

For billions of years before electric light was invented, life on Earth evolved under the pattern of light during the day and darkness during the night. Through evolution, nearly all organisms internalized the temporal rhythm of Earth’s 24-hour rotation and evolved self-sustaining biological clocks...

Full description

Saved in:
Bibliographic Details
Published in:Endocrinology (Philadelphia) 2022-02, Vol.163 (2), p.1
Main Authors: Tonsfeldt, Karen J, Mellon, Pamela L, Hoffmann, Hanne M
Format: Article
Language:English
Subjects:
Animals
Biological clocks
Circadian Clocks
Circadian rhythm
Circadian Rhythm - genetics
Circadian Rhythm - physiology
Circadian Rhythm Signaling Peptides and Proteins
Circadian rhythms
Darkness
Disruption
Earth rotation
Endocrinology
Evolution
Female
Fertility
Follicle-stimulating hormone
Glycoproteins
Gonadotropin-Releasing Hormone
Hypothalamus
Kisspeptins
Light
Light effects
Luteinizing hormone
Luteinizing Hormone - metabolism
Male
Mini-Review
Nerve Net - physiology
Neural networks
Neurons
Neurons - physiology
Neuropeptides - physiology
Ovulation
Physiological aspects
Rodentia
Suprachiasmatic Nucleus - physiology
Transcription Factors - physiology
Vasoactive intestinal peptides
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:For billions of years before electric light was invented, life on Earth evolved under the pattern of light during the day and darkness during the night. Through evolution, nearly all organisms internalized the temporal rhythm of Earth’s 24-hour rotation and evolved self-sustaining biological clocks with a ~24-hour rhythm. These internal rhythms are called circadian rhythms, and the molecular constituents that generate them are called molecular circadian clocks. Alignment of molecular clocks with the environmental light-dark rhythms optimizes physiology and behavior. This phenomenon is particularly true for reproductive function, in which seasonal breeders use day length information to time yearly changes in fertility. However, it is becoming increasingly clear that light-induced disruption of circadian rhythms can negatively impact fertility in nonseasonal breeders as well. In particular, the luteinizing hormone surge promoting ovulation is sensitive to circadian disruption. In this review, we will summarize our current understanding of the neuronal networks that underlie circadian rhythms and the luteinizing hormone surge.
ISSN:0013-7227
1945-7170
DOI:10.1210/endocr/bqab268