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Relationship between Birth Weight and Future Cardiovascular Risks in Japanese in View of the Developmental Origins of Health and Disease (DOHad) Theory

[See article vol. 29 : 188-199] Metabolic syndrome is a combination of cardiovascular risk factors that, in turn, increase the risk of developing coronary heart disease and cerebrovascular disease. Lifestyle-related diseases may occur as a result of the interaction between genetic disposition and li...

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Published in:Journal of Atherosclerosis and Thrombosis 2022/02/01, Vol.29(2), pp.146-147
Main Author: Katsuragi, Shinji
Format: Article
Language:English
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Summary:[See article vol. 29 : 188-199] Metabolic syndrome is a combination of cardiovascular risk factors that, in turn, increase the risk of developing coronary heart disease and cerebrovascular disease. Lifestyle-related diseases may occur as a result of the interaction between genetic disposition and lifestyle, but the incidence of every lifestyle-related disease cannot be explained only by this idea. Poor nutrition in early life has been suggested to increase susceptibility to the effects of an affluent diet. The developmental origins of health and disease (DOHad) theory suggests that dispositions for health and development of disease are formed during the fetal/infant period. Umemoto et al. showed a negative relationship between the birth weight and the risks of hypertension and glucose tolerance in middle-aged individuals.
ISSN:1340-3478
1880-3873
DOI:10.5551/jat.ED158