Hybrid total-body pet scanners—current status and future perspectives

Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In the past years, especially PET systems have seen a trend towards an enlarged axial field of view (FOV), up to a factor of ten. Methods Conducting a thorough literature research, we summarize the status quo of conte...

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Bibliographic Details
Published in:European journal of nuclear medicine and molecular imaging 2022-01, Vol.49 (2), p.445-459
Main Authors: Nadig, Vanessa, Herrmann, Ken, Mottaghy, Felix M., Schulz, Volkmar
Format: Article
Language:English
Subjects:
Cardiology
Computed tomography
Field of view
Gantry cranes
Humans
Imaging
Medical imaging
Medicine
Medicine & Public Health
Nuclear Medicine
Oncology
Orthopedics
Positron emission tomography
Positron Emission Tomography Computed Tomography
Positron-Emission Tomography - methods
Radiology
Review
Review Article
Scanners
Sensitivity
Technology
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Summary:Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In the past years, especially PET systems have seen a trend towards an enlarged axial field of view (FOV), up to a factor of ten. Methods Conducting a thorough literature research, we summarize the status quo of contemporary total-body (TB) PET/CT scanners and give an outlook on possible future developments. Results Currently, three human TB PET/CT systems have been developed: The PennPET Explorer, the uExplorer, and the Biograph Vision Quadra realize aFOVs between 1 and 2 m and show a tremendous increase in system sensitivity related to their longer gantries. Conclusion The increased system sensitivity paves the way for short-term, low-dose, and dynamic TB imaging as well as new examination methods in almost all areas of imaging.
ISSN:1619-7070
1619-7089
DOI:10.1007/s00259-021-05536-4